The problem of premature delivery in modern obstetrics

Abstract

In obstetrics, one the most discussed issue is premature delivery followed by morbidity and mortality of newborns increased up to 1.5-2 times as compared with case of full-term pregnancy. Despite valuable achievements on diagnostics, prevention, treatment of menace of premature delivery and organization of departments of intensive therapy of premature newborns, no country can significantly decrease rate of premature delivery and its aftermaths. The article summarizes the results of original studies and international achievements relating issues of premature delivery. The ways of perspective studies of prevention of premature miscarriage.

Keywords

premature delivery / reanimation of newborn / perinatal mortality / preconception preparation

References

[1] Martin J.A. et al. National Vital Statistics Reports. 2006; 55: 1-104.

[2] Healthy People Objectives. 2010.

[3] ACOG Practice Bulletin. Prediction and Prevention of PB. № 130, oct. 2012.

[4] Blencowe H., Cousens S., Oestergaard M. et al. National, regional and worldwide estimates of preterm birth. Lancet. 2012; 379(9832): 2162-72.

[5] Costeloe K., Henessy E., Haider S. et al. Short term outcomes after extreme preterm birth in England: comparison of two birth cohorts in 1995 and 2006 (the EPICure studies). Br Med. J. 2012; 345: e7976.

[6] Pignotti M.S., Berni R. Extremely preterm births: end-of-life decisions in European countries. Arch. Dis. Child. Fetal Neonatal Ed. 2010; 95(4): F273-6.

[7] Zeitlin J., Ancel P.Y., Delmas D., Breart G., Papiernik E. EPIPAGE and MOSAIC lie-de-France Groups. Changes in care and outcome of very preterm babies in the Parisian region between 1998 and 2003. Arch. Dis. Child. Fetal Neonatal Ed. 2010; 95(3): F188-93.

[8] Zlatohlavkova B., Kytnarova J., Kubena A.A. et al. Five-year survival without major disability of extremely preterm infants born at 22-27 weeks' gestation admitted to NICU. Acta Pediatr. 2010; 99: 1618-23.

[9] Gallagher K., Martin J., Keller M., Marlow N. European variation in decision-making and parental involvement during preterm birth. Arch. Dis. Child. Fetal Neonatal Ed. 2014; Feb 19. doi: 10.1136.

[10] Bergella T.M., Bernet V. El Alama S. et al. Perinatal care at the limit of viability between 22 and 26 completed weeks of gestation in Switzerland. Swiss Med. Wkly. 2011; 141: w13280.

[11] Wilkinson A.R., Ahluwalia J., Cole A. et al. Management of babies born extremely preterm at less than 26 weeks of gestation: a framework for clinical practice at the time of birth. Arch. Dis. Child. Fetal Neonatal Ed. 2009; 94: F2-5.

[12] Sheldon T. Dutch doctors are told to be more aggressive in treating extremely premature babies. Br. Med. J. 2010; 341: e5503.

[13] Pignotti M.S., Donzelli G. Perinatal care at the threshold of viability: an international comparison of practical guidelines for the treatment of extremely preterm births. Pediatrics. 2008; 121(1): e191-8.

[14] Oncel M.Y., Arayici S., Celen S. et al. The association of a cervical length of №25 mm in high-risk pregnancies on neonatal morbidity and mortality in preterm infants. Arch. Gynecol. Obstet. 2013; 287(5): 893-9.

[15] Коваленко А.Е. Угрожающие преждевременные роды. Верификация диагноза: Автореф. дисс.. канд. мед. наук. М.; 2013.

[16] Riboni F., Vitlo A., Dell'avanzo M. et al. Biochemical markers predicting preterm delivery in symptomatic patients: phosphorylated insulin-like growth factor binding protein-1 and fetal fibronectin. Arch. Gynecol. Obstet. 2011; 284(6): 1325-9.

[17] Eroglu D., Yanik F., Oktem M. et al. Prediction of preterm delivery among women with threatened preterm labor. Gynecol Obstet Invest. 2007; 64(2): 109-16.

[18] Ting H.S., Chin P.S., Yeo G.S., Kwek K. Comparison of bedside test kits for prediction of preterm delivery: phosphorylated insulin-like growth factor binding protein-1 (pIGFBP-1) test and fetal fibronectin test. Ann. Acad. Med. Singapore. 2007; 36(6): 399-402.

[19] Ness A., Blumenfeld Y., Sung J.F. Preterm labor. In: Berghella V., ed. Preterm birth. Prevention and management. Wiley-Blackwell; 2010: 198-216.

[20] Коваленко А.Е., Калинина Н.И., Алексеенкова М.В., Панина О.Б., Савельева Г.М. Биохимические маркеры угрожающих преждевременных родов. Акушерство и гинекология. 2013; 3: 43-7.

[21] Romero R., Nicolaides K., Conde-Agudelo A. et al. Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic review and metaanalysis of individual patient data. Am. J. Obstet. Gynecol. 2012; 206(2): 124.

[22] Di Renzo G.C., Giardina I., Clerici G., Mattei A., Alajmi A.H., Gerli S. The role of progesterone in maternal and fetal medicine. Gynecol. Endocrinol. 2012; 28(11): 925.

[23] Шалина Р.И., Плеханова Е.Р. Комплексная терапия беременных с угрозой преждевременных родов. Вопросы гинекологии, акушерства и перинатологии. 2007; 6(1): 33-41.

[24] Conde-Agudelo A., Romero R., Kusanovic J.P. Nifedipine in the management of preterm labor: a systematic review and metaanalysis. Am. J. Obstet. Gynecol. 2011; 204(2): 134.

[25] Conde-Agudelo A., Romero R. Antenatal magnesium sulfate for the prevention of cerebral palsy in preterm infants less than 34 weeks' gestation: a systematic review and metaanalysis. Am. J. Obstet. Gynecol. 2009; 200(6): 595-609.

[26] ACOG Practice Bulletin. Management of preterm labor. № 127, jun. 2012.

[27] Савельева Г.М., Панина О.Б., Бугеренко Е.Ю. и др. Оценка кровотока в системе мать-плацента-плод в ранние сроки беременности и внутриматочного кровообращения в прегравидарном периоде. Журнал акушерства и женских болезней. 2012; 1: 73-9.

RIGHTS & PERMISSIONS

Eco-Vector