THE CONDITION OF PROCESSES OF PEROXIDATION OF LIPIDS AND ANTIOXIDANT SYSTEM AND CLINICAL CHARACTERISTICS OF CHILDREN BORN IN PARENTS SUFFERING OF DIABETES MELLITUS TYPE I

N. P Mikayeliyan; A. E Gurinova; A. V Mikayeliyan; S. V Novikova

doi:10.17816/rmj38161

Russian Medicine ›› 2013, Vol. 19 ›› Issue (5) : 33 -36. DOI: 10.17816/rmj38161

Articles

research-article

THE CONDITION OF PROCESSES OF PEROXIDATION OF LIPIDS AND ANTIOXIDANT SYSTEM AND CLINICAL CHARACTERISTICS OF CHILDREN BORN IN PARENTS SUFFERING OF DIABETES MELLITUS TYPE I

Author information +

History +

PDF

Abstract

The article deals with results of study of processes of peroxidation of lipids and antioxidant defense in 29 children born in parents suffering of diabetes mellitus type I. It is demonstrated that in these children antiradical defense is stronger than in children with diabetes mellitus type I. The reinforcement of antioxidant defense in children born in parents suffering of diabetes mellitus type Ican promote the activation of defense factors with the development of reactions of adaptive character. The foundation of human health is developed in childhood. The processes of formation of morphologic functional status of child, growth and differentiation of tissues mainly depend on presence of diseases and conditions and effect of metabolic processes.

Keywords

free radical / adaptation / diabetes mellitus / antioxidant defense / peroxidation

Cite this article

Download citation ▾

N. P Mikayeliyan, A. E Gurinova, A. V Mikayeliyan, S. V Novikova. THE CONDITION OF PROCESSES OF PEROXIDATION OF LIPIDS AND ANTIOXIDANT SYSTEM AND CLINICAL CHARACTERISTICS OF CHILDREN BORN IN PARENTS SUFFERING OF DIABETES MELLITUS TYPE I. Russian Medicine, 2013, 19(5): 33-36 DOI:10.17816/rmj38161

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Балаболкин М.И. Диабетология. М.: Медицина; 2000.

[2]	Дедов И.И., Шестакова М.В. Сахарный диабет: диагностика, лечение, профилактика. М.: МИА; 2011: 20.

[3]	Martin-Gallan P., Carrascosa A., Gussinye M., Dominguez C. Biomarkers of diabetes-associated oxidative stress and antioxidant status in diabetic patients with or without subclinical complications. Free Rad. Biol. Med. 2003; 34: 1563—74.

[4]	Гаврилов В.Б., Мишкорудная М.И. Спектрофотометрическое определение содержания гидроперекисей липидов в плазме крови. Лабораторное дело. 1983; 3: 33—5.

[5]	Yagi Y., Matsuda M., Yagi K. Formation of lipoperoxide in isolated sciatic nerve by chinophorm-ferric chelate. Experimentia. 1976; 32 (7): 905—6.

[6]	Anderson M.E. Determination of glutathione and glutathione sulfide in biological samples. Methods Enzymol. 1985; 113: 548—55.

[7]	Волчегорский И.А., Налимов А.Г., Яровинский Б.Г., Лифшиц Р.И. Сопоставление различных подходов к определению продуктов перекисного окисления липидов в гептан-изопропанольных экстрактах крови. Вопросы медицинской химии. 1989; 1: 127—31.

[8]	Меньщикова Е.Б., Зенков Н.К., Ланкин В.З. и др. Окислительный стресс: Патологические состояния и заболевания. Новосибирск: АРТА; 2008.

[9]	Биленко М.В. Ишемические и реперфузионные повреждения органов. М.: Медицина; 1989.

[10]	Зенков Н.К., Ланкин В.З., Меньщикова Е.Б. Окислительный стресс: Биохимический и патофизиологический аспекты. М.: МАИК "Наука/Интерпериодика"; 2001.

[11]	Furukawa S., Fujita T., Shimabucuro M. Increased oxidative stress in obesity and its impact on metabolic syndrome. Clin. Invest. 2004; 114 (12): 1752—61.