THE LIMITATION OF METABOLIC AND INFLAMMATORY ALTERATIONS IN POST-SURGERY PERIOD: THE ROLE OF FIELD BLOCK ANESTHESIA AND ANALGESIA

P. A Lyuboshevskiy; A. V Zabusov; A. L Timoshenko; D. V Korovkin

doi:10.17816/rmj38131

Russian Medicine ›› 2013, Vol. 19 ›› Issue (5) : 15 -19. DOI: 10.17816/rmj38131

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THE LIMITATION OF METABOLIC AND INFLAMMATORY ALTERATIONS IN POST-SURGERY PERIOD: THE ROLE OF FIELD BLOCK ANESTHESIA AND ANALGESIA

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Abstract

The limitation of surgery stress-response is considered as one the main tasks of anesthesia and post-surgery intensive therapy. The article deals with evaluation of intensity of neuro-endocrinal, metabolic and inflammatory alterations after abdominal operations depending on type of anesthesia. The sample of 260 patients was divided on groups depending on type of anesthesia (total intravenous anesthesia as is, combined with epidural or spinal anesthesia). The analysis was applied to concentration of cortisol, glucose, lactate, cytokines, nitrogen excretion with urine and intensity of post-surgery pain syndrome. During post-surgery period significant increase of concentration of cortisol, glucose and lactate and pro inflammatory and antiinflammatory cytokines was established. The application of both spinal and epidural anesthesia during operation significantly decreased intensity of these alterations and limited nitrogen excretion. Besides, the epidural analgesia provided more adequate post-surgery pain relief.

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abdominal surgery / types of anesthesia / post-surgery pain relief

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P. A Lyuboshevskiy, A. V Zabusov, A. L Timoshenko, D. V Korovkin. THE LIMITATION OF METABOLIC AND INFLAMMATORY ALTERATIONS IN POST-SURGERY PERIOD: THE ROLE OF FIELD BLOCK ANESTHESIA AND ANALGESIA. Russian Medicine, 2013, 19(5): 15-19 DOI:10.17816/rmj38131

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