THE POSSIBILITIES OF CONFOCAL LASER ENDOMICROSCOPY IN DIAGNOSTICS OF BARRETT ESOPHAGUS

V. A Solodkiy; Yu. V Sinev; O. V Ivanova; I. B Grunin; P. B Kolomatskaya

doi:10.17816/rmj38094

Russian Medicine ›› 2013, Vol. 19 ›› Issue (1) : 33 -36. DOI: 10.17816/rmj38094

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THE POSSIBILITIES OF CONFOCAL LASER ENDOMICROSCOPY IN DIAGNOSTICS OF BARRETT ESOPHAGUS

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Abstract

The endomicroscopy using confocal laser scanning system Cellvizio (Mauna Kea Technologies, France) was applied to 51 patients with suspicion on Barrett esophagus during standard esophagogastroduodenoscopy. This is a new non-invasive technique which by the use of diminutive confocal endomicroscope in the real-time mode provides an opportunity to visualize various types of epithelium cells and to detect cell and vessel alterations typical for Barrett esophagus and related with it neoplastic transformations of epithelium. The data is compared concerning the endomicroscopic and morphologic reports. The Barrett esophagus and associated neoplasia can be detected with sensitivity of 97.1 and 92.7% and specificity of 94.1 and 98.2% correspondingly (accuracy 96.6 and 97.2%).

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Cellvizio / Barrett esophagus / intestinal metaplasia / adenocarcinoma of esophagus / confocal laser endomicroscopy / Cellvisio

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V. A Solodkiy, Yu. V Sinev, O. V Ivanova, I. B Grunin, P. B Kolomatskaya. THE POSSIBILITIES OF CONFOCAL LASER ENDOMICROSCOPY IN DIAGNOSTICS OF BARRETT ESOPHAGUS. Russian Medicine, 2013, 19(1): 33-36 DOI:10.17816/rmj38094

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