Association of epicardial adpose tissue with coronary atherosclerosis in patients with metabolic syndrome

Abstract

Patients with metabolic syndrome (MS) are at high cardiovascular risk. Having hormonal activity and close anatomic and functional relationships to the myocardium, epicardial adipose tissue plays an important role in the development and progression of coronary atherosclerosis. Therefore, estimation of the epicardial adipose tissue (EAT) thickness may serve as a marker for early cardiovascular events in patients with MS. The study enrolled 96 males aged 56.94+0.97 years with ischemic heart disease in the presence of MS. The authors made anthropometric measurements, assessed metabolic risk factors, estimated hormones in visceral adipose tissue, and performed echocardiography and coronary angiography (CAG). Patients with MS and an EAT thickness of ≥ 7 mm had marked metabolic and hormonal disturbances and significant coronary bed lesion as evidenced by CAG.

Keywords

metabolic syndrome / coronary heart disease / epicardial adipose tissue / adipokines

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