Uric acid as a prognostic marker in elderly patients with an exacerbation of coronary artery disease

Abstract

The search for causal factors that can influence the prognosis after an acute coronary syndrome in elderly patients is a critical task. This study aimed to assess the correlation between increased uric acid levels with the incidence of adverse outcomes in patients over 75 years of age with history of acute coronary syndrome. Medical Records of 343 patients over 75 years old with history of acute coronary syndrome were retrospectively reviewed. Clinical characteristics and laboratory data upon admission, whether deceased or survived, were also analyzed. When carrying out multivariate analysis, following factors independently associated with total mortality were analyzed: aortic stenosis, atrial fibrillation, hyperglycemia, and acute heart failure at the moment of the index event, hyperuricemia, and percutaneous coronary intervention at the time of hospitalization caused by the index event. Thus, an increase in the level of uric acid is an independent predictor of lethality in the senior age group patients.

Keywords

acute coronary syndrome / uric acid / adverse outcomes

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