Oxidative stress and inflammation in COVID-19 pathogenesis

Vladimir G. Kukes , Olga K. Parfenova , Nikita G. Sidorov , Yuri V. Olefir , Albina А. Gazdanova

Russian Medicine ›› 2020, Vol. 26 ›› Issue (4) : 244 -247.

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Russian Medicine ›› 2020, Vol. 26 ›› Issue (4) : 244 -247. DOI: 10.17816/0869-2106-2020-26-4-244-247
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Oxidative stress and inflammation in COVID-19 pathogenesis

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Abstract

This study discusses the role of oxidative stress and inflammation in the development of severe acute respiratory syndrome (SARS) associated with COVID-19 caused by the novel SARS-CoV-2 coronavirus. An analysis of the literature revealed that the development of respiratory viral infections, including COVID-19, is usually accompanied by the accumulation of acidic metabolic products in the blood and tissues and, accordingly, oxidative stress and increased levels of cytokines. In this regard, it seems appropriate to use the second-generation low-toxic antioxidant Ethoxidol, manufactured in Russia, which reduces the intensity of inflammation, and also improves blood oxygen saturation.

Keywords

review / COVID-19 / oxidative stress / inflammation / cytokines / antioxidants / Ethoxidol

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Vladimir G. Kukes, Olga K. Parfenova, Nikita G. Sidorov, Yuri V. Olefir, Albina А. Gazdanova. Oxidative stress and inflammation in COVID-19 pathogenesis. Russian Medicine, 2020, 26(4): 244-247 DOI:10.17816/0869-2106-2020-26-4-244-247

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