The creation of special state environmental structures (Goskompriroda, the Ministry of Ecology), the activation of the public movement for the protection of nature, the formation of a number of scientific and technical programs of environmental orientation at the federal, academic, and sectoral levels - all this testifies to the growing concern of the community for the fate of generations.

The picture of the pathogens and plant interaction is presented. That is: recognition; the influence of different hydrolases produced by pathogens on plant biopolimers and lipids; elicitors and phytoalexins formation; pathogen-induced proteins synthesis in plants; induction of supersensitivity in cells, surrounding the pathogen infection area; the influence of plant enzymes and toxins on pathogens and finally — working out plant tissues resistance against pathogens (viruses, bacteria and fungi).

The complex research of ecological situation near the automobile bridge across the Volga river showed the serious ecological tension after the solid dam construction. The negative tendencies will progress without corresponding measures. The economical damage as the result of biological resources lost will be about 280 mln. rubles (according to 1991 year data).

Here the results of the long-term research in the sphere of the role of high aquatic plants in the acceleration of the process of self-purification of water are adduced. We propose the creation of bioengineer constructions for the purpose of prevention surface-waters from pollution.

The three year researches of Clethrionomys glareolus and Drosophila melanogastcr populations are presented. The experiment was pursued in Nizhnekamsk, the controlled region was situated in Sarali of the Volga—Kama zapovednic without atmosphere pollutions. There has been shown that the levels of prenatal mortality and potential fecundity are arised in the Nizhnekamsk populations. The latter is thought to be the compensation mechanism which stabilizes the reproduction of population. There has been stown that the induced mutagenesis (dominant and recessive lethal mutations) in the populations of Drosophila which were exposed in Nizhnekamck.

Presented are the results of 4-years investigation in shallows of the rivers Mjosha and Kama. The sources and distribution of heavy metals in water, bottom deposits, plants, fito- and zooplankton, invertabrates, fishes and amphibians are discussed.

Three marked zones in Kazan district of Kuibyshev reservoir differ reliably in heavy metals concentration in bottom deposits. The maximum metals accumulation was noticed in shallow deposits. The usage of biological test-objects is advisable to reveal the local polution centres boundaries.

The content and distribution of metals (Pb, Cu, Ni, Zn, Cr, Mn) in soils and alluvial deposits of the islands of Kuibyshev reservoir are studied on the base of geochemical approach- ment. The main sources of metals in islands ecosystems are discussed. The noticed regional difference in metal’s contents in soils between Volga and Kama islands is due to rock composition, grain sixe of deposits and soil formation regimes.

The revealed peculiarities of heavy metals distribution in biosphere components of the East Kama region define its «background» concentrations. Soil-geochemical division of the territory into districts is the basis for environmental monitoring taking into account the speciality of population health breaches.

There has been shown the natural nidus tickal encephalus West Nile and Syndbys fever existance in the Kuibyshev reservoir island systems and Grippotiphyis, Pomon and Gebdomadys serodroups as well. The additional data about wide expansion of nidus GLPS on the islands and rabbit-feber, infection currency sporadical character in the small mammalians populations is recieved.

Redundant serum essential heavy metals in children with atopic eczema, bacterial infections and burdened heredity is due to influence of surrounding contaminations as well as expressed disbalance of zinc, copper and iron. Redundancy of studied heavy metals leads to injury of immune system. Severity of the atopic eczema and bacterial diseases is considerably determined by expression of disbalance.

The peritoneostomy method is improved and tested in 42 patients with acute purulent general peritonitis. It’s therapeutic effect is explained by the possibility of performing the continuous controlled sanitation of the abdominal cavity, prevention of pulmonary complications in postoperative period, and protection of abdominal wall tissue in incision region from secondary infection. The method permits to decrease efficiently the manifestation of endogenous intoxication, the number of postoperative complications, to reduce the terms of stationary treatment and lethality. The indications to the application of this method in hospital are formulated.