The literature on the pathogenesis of primary glaucoma is extremely extensive, and there are a wide variety of, often totally conflicting, views. A wealth of evidence has accumulated describing the general state of the body in glaucoma patients and the local changes in the eye. The individual parts of the pathogenesis of the glaucomatous process, especially of closed angle glaucoma, have been studied in detail. However, there is currently no general theory of pathogenesis that satisfactorily explains all of the above key facts. Below we present a concept which we have reported and discussed at the joint meeting of the Problem Commission for Ophthalmology of the RSFSR Ministry of Health and the Scientific Council of the Moscow Helmholtz Moscow Research Institute of Eye Diseases in May 1970.

For the success of the clinical application of cardiac defibrillation it is very important to understand the causes of 'post-conversion' rhythm abnormalities. One of these is that electrical shocks can cause myocardial K loss. It is therefore recommended that in such cases K, panangin (potassium magnesium aspartate), should be administered. Electrical shocks can also irritate the intrathoracic sympathetic and parasympathetic nerves.

The activation of the sympathetic nervous system, which increases heart rate and myocardial oxygen demand, is now considered to be of great importance in the onset of angina attacks. The sympathetic nervous system activates cells through its mediators, whose interaction with cell receptors results in a specific response.

The widespread introduction of modern methods of general anaesthesia into medical practice has significantly expanded the indications for surgical interventions under anaesthesia in hypertensive patients. In this regard, the choice of the main anesthetic for anaesthesia in persons with arterial hypertension is of particular importance, as its pharmacodynamic properties largely determine the changes in the circulatory system observed during surgery and anaesthesia.

Circulatory insufficiency continues to be a major problem in cardiology. Its severity and the ability to compensate for impaired cardiac function in patients with cardiac defects not only determine whether these patients return to work, but also their vitality.