Study of antiacidotic activity of dimefosfon
I. A. Studentova , I. V. Zaikonnikova , A. O. Vizel , R. S. Garaev
Kazan medical journal ›› 1989, Vol. 70 ›› Issue (2) : 118 -120.
Study of antiacidotic activity of dimefosfon
Acidotic shift of acid-base status is an important pathogenetic link in many diseases. Its urgent correction in urgent patients is usually carried out by intravenous administration of sodium bicarbonate or trisamine, chemically neutralizing excess acidic blood metabolites. However, these drugs do not eliminate intracellular pH shifts, do not affect the metabolic processes in the tissues that caused acidosis. They can be used only under hospital conditions under constant monitoring of acid-base status, requiring the use of special equipment.
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