Possibilities of immunocytochemistry in differential cytogenetic diagnosis of thyroid cancer and its metastases
Z. A. Afanas'yeva , S. V. Petrov , G. N. Khairutdinova , I. V. Balatenko , T. V. Guryanova
Kazan medical journal ›› 2000, Vol. 81 ›› Issue (4) : 276 -280.
Possibilities of immunocytochemistry in differential cytogenetic diagnosis of thyroid cancer and its metastases
To determine the diagnostic value of immunocytochemistry in the thyroid cancer the immunomorphological examinations (immunocytochemical and immunohistochemical) are carried out in 61 patients with the thyroid cancer, thyroid lymphoma and cancer metastases without the primary focus. Immunocytochemistry is combined with fine needle aspiration biopsy under ultrasonic control in some patients with nonpalpable tumors to receive representative material. The true diagnosis of the thyroid cancer is determined in 92% and 100% of the cases with the help of immunocytochemistry and postoperative immunohistochemistry, respectively. The high information value of immunochemistry is proved in the diagnosis of the thyroid cancer, thyroid lymphosarcomas and in searching the primary focus in metastatic carcinoma without the primary focus.
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