Influence of chloditan on the content of glycosaminoglycans in the blood and liver of rats with alloxan diabetes

A. A. Batting , E. G. Butolin

Kazan medical journal ›› 2000, Vol. 81 ›› Issue (3) : 192 -194.

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Kazan medical journal ›› 2000, Vol. 81 ›› Issue (3) : 192 -194. DOI: 10.17816/kazmj96703
Theoretical and clinical medicine
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Influence of chloditan on the content of glycosaminoglycans in the blood and liver of rats with alloxan diabetes

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Abstract

Hypoglucocorticoidemia caused by systemic injection of chloditane {[2(chlorphenil)-2-(4- chlorphenil)-l]-l dichlorethane} promotes normalizing the content of glycosaminoglykanes in blood of rats with alloxan diabetes. The increase of concentration of the total glycosaminoglykanes in liver tissue of these rats on the 30th day occurs as a result of the accumulation. The determination of the content W sulphatized glycosaminoglykanes can be used to reveal the metabolic disorders in the connective matrix in alloxan diabetes.

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A. A. Batting, E. G. Butolin. Influence of chloditan on the content of glycosaminoglycans in the blood and liver of rats with alloxan diabetes. Kazan medical journal, 2000, 81(3): 192-194 DOI:10.17816/kazmj96703

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