Influence on the process of glycation of serum albumin of synthetic antidiabetic agents

Abstract

Synthetic antidiabetic agents (glyphormin, glyclaside, glycvidone, glybenclamide) in incubation of high concentrations of glucose with human serum albumin in experiments in vitro can diminish glycation process. In mild glycation regime the effect of agents becomes more prolonged and pronounced. The protein glycation leved in constant glucose concentration in rats with alloxan induced diabetes decreases while injecting them with glyphormin, glycvidone and and glybenclamide during a month

Keywords

Kazan Medical archive

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