Experimental and clinical substantiation of the use of xymedon as an antioxidant in the complex treatment of patients with chronic osteomyelitis
K. V. Malyshev
Kazan medical journal ›› 2000, Vol. 81 ›› Issue (1) : 13 -17.
Experimental and clinical substantiation of the use of xymedon as an antioxidant in the complex treatment of patients with chronic osteomyelitis
The antioxidant activity of blood plasma is studied in patients with chronic osteomyelitis. The experimental data on the effect of antioxidants of xymedone and methyluracil on the basic free radicals, peroxide oxidation of li poids and chemoluminescence of peritoneal macrophages of rats made it possible to justify the use of drugs in the complex treatment of patients in pre- and postoperative period. As a result of the use of xymedone in the complex treatment the blood indices improved, antioxidant plasma activity increased in 25 patients of the basic group. In patients of the control group taking methyluracil the efficiency of the treatment was less significant
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