Use of anapriline for radiopaque diagnosis of sphincter Oddy spasm
A. R. Novakovsky
Kazan medical journal ›› 1987, Vol. 68 ›› Issue (3) : 167 -170.
Use of anapriline for radiopaque diagnosis of sphincter Oddy spasm
Many researchers point to frequent lesion of the sphincter apparatus of the terminal choledochal region in biliary tract diseases. Thus, spastic state of Oddi sphincter occurs in 4.2-21.9% of cases that depends on a contingent of patients and type of biliary tract pathology.
Diagnostics of spastic state of Oddi sphincter is based on dynamics of contrast substance accumulation, and also on reaction to spasmolytic drugs: nitroglycerin, amylnitrite etc. Nitroglycerin and amyl nitrite are antispasmodics, indirectly acting on smooth muscles of biliary tracts and having unstable effect.
Based on observation of O.S. Kochnev and V.N. Biryaltsev about the influence of ß-adrenoblocker anapriline on the contractile function of Oddi sphincter (author's certificate No 1082404), we used this drug in the process of infusion cholangiography in 80 patients with biliary system pathology.
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