On the role of the spleen in changes in blood composition in splenomegalic cirrhosis of the liver
I. Ya. Ashkinazi
Kazan medical journal ›› 1960, Vol. 41 ›› Issue (4) : 87 -88.
On the role of the spleen in changes in blood composition in splenomegalic cirrhosis of the liver
49 patients with splenomegalic cirrhosis of the liver (19 of them after splenectomy) and 18 healthy individuals were examined. The parameters of peripheral blood and bone marrow, osmotic resistance of erythrocytes and leukocytes to hypotonic NaCl solution, immunological Coombs' reactions, cold agglutination of erythrocytes, leukoagglutination) were studied. Studies have shown that in splenomegalic cirrhosis of the liver, the pathologically altered spleen is of great importance in the development of anemia and leukopenia.
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