Mechanisms of changes in the oxygen transport function of erythrocytes in patients with chronic ischemic heart disease complicated by circulatory insufficiency

Abstract

One of the early and characteristic reactions to hypoxia, including in patients with circulatory insufficiency, is an increase in the level of 2,3-diphospho-glycerate (2,3-DPH) of erythrocytes [4, 6, 10, 12], which is formed in the Rapoport - Lubering cycle and is an offshoot of glycolysis of erythrocytes. The features of the interaction of hemoglycolysis and the Rapoport — Lubering cycle in patients with circulatory insufficiency have not been studied before. Knowledge of such features makes it possible to determine the degree of participation of erythrocytes in the development of hypoxia in patients at different stages of circulatory insufficiency.

Keywords

Kazan Medical archive

References

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