The effect of specific inhibition of Hageman factor on contact-activated fibrinolysis
I. M. Baishev
Kazan medical journal ›› 1984, Vol. 65 ›› Issue (3) : 230 -230.
The effect of specific inhibition of Hageman factor on contact-activated fibrinolysis
Highly purified factor XII zymogen (Hageman factor) of human blood plasma, when bound to a foreign surface, is capable of self-activation by intramolecular proteolysis. The resulting active Hageman factor stimulates blood clotting along the internal and external pathways, kininogenesis and fibrinolysis. The aim of our work was to study contact-induced fibrinolysis with selective inhibition of factor XIIa in blood plasma.
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