The effect of semipermeable membranes on the contact activation of blood clotting during programmed hemodialysis

S. A. Mukhametzyanov; B. S. Eltsephon; L. G. Popova; V. A. Gaponenko; T. P. Ruban; M. X. Vakhitova; N. A. Vengerova

doi:10.17816/kazmj88101

Kazan medical journal ›› 1983, Vol. 64 ›› Issue (5) : 350 -352. DOI: 10.17816/kazmj88101

Clinical medicine

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The effect of semipermeable membranes on the contact activation of blood clotting during programmed hemodialysis

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Abstract

Currently, hemodialysis is one of the effective methods of treatment of end-stage chronic renal failure (CRF). As is known, with this method of purification, the patient's blood comes into direct contact with a semipermeable membrane over a large area, through which nitrogenous slags are removed from the body. Despite the fact that in order to prevent blood clotting in the extracorporeal system, its heparinization is carried out, sometimes there is thrombosis of the dialyzer and its highways. A similar complication was observed by M. D. Javad-Zade and P. S. Malkov (1978) in 1% of cases, and I. S. Yarmolinsky and X. K. Chernevskis (1978) - in 2.5%. In this regard, all new membranes created for hemodialysis need to be studied by their interaction with blood.

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S. A. Mukhametzyanov, B. S. Eltsephon, L. G. Popova, V. A. Gaponenko, T. P. Ruban, M. X. Vakhitova, N. A. Vengerova. The effect of semipermeable membranes on the contact activation of blood clotting during programmed hemodialysis. Kazan medical journal, 1983, 64(5): 350-352 DOI:10.17816/kazmj88101

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