The use of thymalin for the treatment of thermal injury

Abstract

It has been shown that the use of a low-molecular polypeptide from thymus cells - thymalin - in patients with burns shortens the time of the first autoplasty, improves the results of engraftment of autografts, increases the number of T-lymphocytes, "active" T-lymphocytes, B-lymphocytes and the concentration of Ig A, reduces complement activity. At the same time, the intensity of intravascular coagulation decreases and fibrinolysis is activated. The most favorable time for the use of thymalin is 6-15 days after thermal injury.

Keywords

burn disease / timalin

References

[1] Балуд а В. П., Баркаган 3. С. и др. Лабораторные методы исследования системы гемостаза. Томск, 1980.

[2] Баркаган 3. С., Еремин Г. Ф. Тер. арх. 1981, 9,

[3] Будажабон Г. Б., Будажабон Н. Г. Лаб. дело. 1981, И.

[4] Козлов В. А., Котов Г. А. и др. Вести, хир., 12.

[5] Кузник Б. И., Хавин- сон В. X. и др. Педиатрия, 1982, 4.

[6] Морозов В. Г., Хавинсон В. X. Докл. АН СССР, 1978, 4.

[7] Хавинсон В. X., Морозов В. Г. Иммунология, 1981, 5.

[8] Bianco, Patrie С. Nussenzweig J. Exp. Med., 1973, 136, 2.

[9] Jon dal M., Wigzel 1 H. J. Exp. Med., 1972, 136, 2.

[10] Kerman R. H., Smith K., Stefani S. S., Ezdinli E. L. Cancer Res., 1976, 36, 9.

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