Change of zinc homeostasis in kidney diseases in children

Abstract

The zinc metabolism in kidney pathology in children is studied. The decrease of serum zinc level connected with its increased excretion, that is identified as deficiency of the excretory type, is revealed. The effect of the increased zinc excretion on the functional state of proximal tubules, tested by the level of aminoaciduria and phosphate reabsorption, as well as on the function of distal tubules, determined by the processes of acido- and ammoniogenesis, is established. The depressive effect of zinc on cellular and humoral immunity links as well as on phagocytic activity of neutrophiles, that is identified as dificiency of immunologic consumption, is established.

Keywords

Kazan Medical archive

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