Detection of autoantibodies in patients with chronic bronchitis

Abstract

In 120 patients with chronic bronchitis and 104 healthy individuals, circulating autoantibodies to the bronchial mucosa were studied. Exacerbation of the chronic inflammatory process in the bronchi is accompanied by a significant increase in autoantibody titers. A direct relationship was found between the level of autoantibodies, the severity and duration of the disease. By the time of discharge from the hospital in some patients, autoantibody titers remain at a high level, often up to six months. Determination of anti-bronchial antibodies in the dynamics of chronic bronchitis can be used to recognize the activity of the inflammatory process and predict its outcome.

Keywords

Chronical bronchitis / antibronchial autoantibodies / Kazan Medical archiv

References

[1] Айзина Н. Л. Гиг. труда, 1980, 3.

[2] Дадабаева Н. А. В кн.: Материалы II Всесоюзн. симпозиума по пробл. «Аллергия и иммунопатология». Львов—Москва, 1971.

[3] Иванова Н. М. В кн.: Аллергологические и иммунологические аспекты при заболеваниях легких. Л., 1975.

[4] Кабисова И. Д., Безденежных А. И. Врач, дело, 1973, 4.

[5] Клемпарская Н. Н., Раева Н. В. Бюлл. экспер. биол., 1961, 5.

[6] Кондратенко Г. П., Гриценко Л. 3., Цыбульник 3. И. Тер. арх., 1976, 12.

[7] Король О. И., Молодцова В. П. Тер. арх., 1977, 10.

[8] Походзей И. В., Иванова Н. М., Смирнова А. М. и др. Тер. арх., 1975, 2.

[9] Сахарчук И. И., Бордонос В. Г. Там же, 1982, 3.

[10] Boyden S. Adv. Immunol., 1966, 5, 1.

RIGHTS & PERMISSIONS

Osipov Y.A.