Features of immunity in patients with diphtheria

S. S. Lebenzon , D. N. Mayansky , E. A. Spiridonova , A. V. Vasyunin , I. V. Altukhova , S. B. Garbuzova

Kazan medical journal ›› 1982, Vol. 63 ›› Issue (5) : 41 -42.

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Kazan medical journal ›› 1982, Vol. 63 ›› Issue (5) : 41 -42. DOI: 10.17816/kazmj64519
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Features of immunity in patients with diphtheria

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Abstract

The indices of humoral and cellular immunity were studied in 10 patients with typical and 7 atypical (carriage) forms of diphtheria infection. The highest level of antibodies (4.25 ± 1.2 AU / ml) was in carriers of diphtheria bacteria, and the lowest (0.07 AU / ml) was in patients with toxic diphtheria. Disturbances in the structure of cellular immunogomeostasis - a decrease in the total number of T-lymphocytes, an increase in Ta-ROK, an increase in the functional activity of phagocytic neutrophils and peripheral blood monocytes - were found in all and were most pronounced in patients with toxic diphtheria. In children, according to epidemiological indications, vaccinated with ADS, while the number of T-lymphocytes was preserved, all other studied parameters turned out to be increased.

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diphtheria infection / immunogomeostasis / phagocytic neutrophils and monocytes / Kazan Medical archiv

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S. S. Lebenzon, D. N. Mayansky, E. A. Spiridonova, A. V. Vasyunin, I. V. Altukhova, S. B. Garbuzova. Features of immunity in patients with diphtheria. Kazan medical journal, 1982, 63(5): 41-42 DOI:10.17816/kazmj64519

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References

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Покровский В. И., Авербах М. М„ Литвинов В. И., Рубцов И. В. Приобретенный иммунитет и инфекционный процесс. М., Медицина, 1979.

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Lebenzon S.S., Mayansky D.N., Spiridonova E.A., Vasyunin A.V., Altukhova I.V., Garbuzova S.B.

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