Chromatographic study of heparin preparations

G. Sh. Chenborisova , A. O. Kiselev

Kazan medical journal ›› 1982, Vol. 63 ›› Issue (3) : 56 -57.

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Kazan medical journal ›› 1982, Vol. 63 ›› Issue (3) : 56 -57. DOI: 10.17816/kazmj62054
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Chromatographic study of heparin preparations

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Abstract

Heparin preparations used in clinics of our country (produced in Minsk, Kaunass, Baku, Hungary and Czechoslovakia) differ in their biological activity. Heparin is a variable molecular weight polymer of about 17,000 daltons. Its monomer unit consists of a-glucuronic acid esterified with another sulfuric acid at carbon 2, glucoseamine esterified with sulfuric acid at carbon 6 and at the amino group of carbon 2, and L-iduronic acid. The remains of glucuronic acid and glucosamine, iduronic acid and glucosamine are linked by glycosidic a (1 -> 4) bonds.

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G. Sh. Chenborisova, A. O. Kiselev. Chromatographic study of heparin preparations. Kazan medical journal, 1982, 63(3): 56-57 DOI:10.17816/kazmj62054

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Chenborisova G.S., Kiselev A.O.

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