Clinical value of the determination of anticardial antibodies in patients with acute myocardial infarction
N. D. Pozdnyak , I. V. Efremova
Kazan medical journal ›› 1982, Vol. 63 ›› Issue (2) : 13 -16.
Clinical value of the determination of anticardial antibodies in patients with acute myocardial infarction
In 281 patients with acute myocardial infarction, the titer of anticardial antibodies was studied using the indirect immunofluorescence method of Koons. With adequate, immunological reactivity, the height of anticardial-antibody titers reflects the extent of necrotic myocardial damage. Their earliest appearance in blood serum (1-2 days of illness) was observed with repeated and recurrent myocardial infarction. Dissociation between the magnitude of necrotic myocardial damage and a low level of anticardial antibodies indicates a "breakdown" of the protective immunological mechanisms and has an unfavorable prognostic value.
acute myocardial infarction / anticardial antibodies / immunofluorescence method / immunological reactivity / Kazan Medical archiv
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