On the question of acid diathesis in ulcerative patients
V. F. Yakimova
Kazan medical journal ›› 1931, Vol. 27 ›› Issue (3) : 230 -239.
On the question of acid diathesis in ulcerative patients
In 1926, almost simultaneously, reports appeared abroad of Balint, with us -the late S. S. 3imnitsky, where the old biochemical theory of Leibe and Surfactants, which explained the formation of stomach ulcers by insufficient neutralization of acidic gastric contents due to a decrease in blood alkalinity, received new coverage. Balint, based on the experimental data of his and his students on patients of the clinic he runs, Zimnitsky, based on the study of the autonomous nervous system in ulcerative patients (ord. Lande) n successful alkaline and insulin therapy, came to the same conclusion in resolving the issue of the pathogenesis of round gastric ulcer, which they consider as a consequence and a kind of identification of tissue acidosis, t. naz. sour diathesis. The consequence of this diathesis, according to Zimnitsky, is dystonia of the autonomic nervous system with a certain increase in vagotonus, accompanying spasmophilia, which is observed in ulcers, cholecystitis, appendicitis and many other spastic conditions of the gastrointestinal tract. This coincidence of the conclusions of two researchers who went completely different ways to resolve the same issue, according to Zimnitsky, is the best proof of the correctness of the conclusion made.
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