Selenium status and lipid peroxides in patients with cardiovascular diseases

Abstract

Selenium concentration in blood and plasma as well as the activity of glutathionperoxidase of erythrocytes and lipid peroxides are studied in patients with neurocirculatory dystonia, ischemic heart disease, hypertrophic and dilatation cardiomyopathy. The reduction of the activity of glutathioperoxidase of erythrocytes and activation of lipid peroxides without blood selenium concentration decrease are revealed in patients with neurocirculatory dystonia. The decrease of blood selenium concentration, the activity of glutathionperoxidase of erythrocytes and activation of lipid peroxides are revealed in patients with ischemic heart disease, dilatation and hypertrophic cardiomyopathy. The content of blood serum selenium is linked with lipid peroxides and magnitude of left ventricle diastolic dimension in patients with dilatation cardiomyopathy. The results obtained suggest selenium particilation in cardiomyopathy and ischemic heart disease pathogenesis aproving the study of selenium-containing drugs utility.

Keywords

Kazan Medical archive

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