Simplified calculation of genetic risk
N. A. Sergeeva
Kazan medical journal ›› 1996, Vol. 77 ›› Issue (5) : 371 -372.
Simplified calculation of genetic risk
Calculating the risk of transmitting a hereditary disease to offspring is important in the practice of medical genetic counseling. Most universal formulas are cumbersome, and their use assumes that the frequency of the mutant gene is already known or is calculated from special tables. Despite the complexity of the calculation procedure, it is necessary to determine the type of inheritance when using information only about sick family members and their kinship relations, taking into account the possibility of incomplete manifestation of the genotype.
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