On the effectiveness of the combined use of antibiotics and pentoxyl in the treatment of purulent wound infection

Abstract

Research data of our department show that purulent staphylococcal processes, difficult to treat because of their complication with Proteus, under the influence of treatment with a combination of penicillin and synthomycin (or levomycetin) proceed more easily and end earlier than those treated with penicillin alone (Melnikov, Gubaidullina, Kutdusova). However, even with the combination of penicillin and synthomycin complete recovery of animals comes not earlier than 4-5 weeks. Such duration of the healing process, we must think, to some extent associated with inhibition of immunological reactions by antibiotics, which contributes to the preservation of proteus in the wound and delays the process of tissue regeneration.
In this regard, the question of reasonable forms and methods of adding any stimulating drugs to antibiotic therapy, providing greater efficiency in the fight against infection, is of interest. In search of such a method we stopped on pentoxyl.

Keywords

Kazan Medical archive

References

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[2] М. З. Губайдуллина. „Комбинированное лечение ассоциированных гнойных инфекций медикаментозным сном и антибиотиками“. Итоговая научная конференция (авторефераты докладов), 1953, декабрь.

[3] X. А. Кутдусова. „Материалы к вопросу лечения гнойных ассоциированных инфекций антибиотиками“. Там же.

[4] В. Н. Лазарев и Г. И. Фелистович. „Пентоксид и его применение при алейкиях“. Медгиз, 1954.

[5] Г. М. Мисевич. „Вестник оториноларингологии“, 3, 46, 1952.

[6] Хвиливицкая, Ульянова, Грех и Черненько. Цит. по Н. В. Лазареву и Г. И. Фелистович. „Пентоксид и его применение при алейкиях“. Медгиз, 1954.

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