Structural organization of the contralateral salivary glands

Abstract

BACKGROUND: It has been established that there are no functional differences between the paired salivary glands, but the presence or absence of structural differences in the contralateral salivary glands remains unknown.

AIM: To determine the presence of features of the contralateral salivary glands’ structural organization, which should be taken into account in the process of differential diagnosis in patients with various diseases of the salivary glands when analyzing sialograms.

MATERIAL AND METHODS: In 60 patients with diseases of the salivary glands, digital subtraction sialography of the parotid (right n=33, left n=26) and submandibular (right n=17, left n=19) glands was performed. The parameters of the paired glands were compared: the number and time of filling of the ducts with the water-soluble non-ionic contrast agent iodixanol. The sample was formed without taking into account gender, age and diseases. Cases with stones or ductal strictures were excluded. The significance of differences was assessed using Student's t-test. The results were considered significant at p ≤0.05.

RESULTS: The contrast time for the parotid glands (n=59) averaged 29.8±8.9 s: on the right — 31.0±8.0 s (n=33), on the left — 28.2±9.6 s (n= 26; t=1.2219); submandibular glands (n=36) — 28.6±11.6 s: on the right — 30.2±14.4 s (n=19), on the left — 27.3±8.3 s (n=17; t= 0.7284). The amount of drug injected into the ducts reflected their volume, which we considered as an accurate characteristic of their structural state. 1.4±0.3 ml of iodixanol (Visipack) was injected into the parotid glands (n=59): on the right — 1.4±0.3 ml (n=33), on the left — 1.4±0.3 ml (n =26; t=0). 1.2±0.3 ml was injected into the submandibular glands (n=35): on the right — 1.2±0.4 ml (n=17), on the left — 1.1±0.3 ml (n=18; t=0.8399). There was no significant difference between the contralateral glands, but there was a significant diffe¬rence between the parotid and submandibular glands (t=3.1247; p ≤0.001). When conducting scientific analysis, data from the contralateral salivary glands could be combined into a single sample. The amount of drug injected into the ducts served as a characteristic of the structural state of the gland.

CONCLUSION: The contralateral salivary glands do not have significant structural differences, and structural changes in the same patient are of the same type.

Keywords

parotid glands / submandibular glands / digital subtraction sialography

References

[1] Shchipskiy AV, Kalimatova MM, Mukhin PN. Secretory function of the contralateral parotid glands. Kazan Medical Journal. 2022;103(6):1034–1039. (In Russ.) DOI: 10.17816/KMJ112128.

[2] Щипский А.В., Калиматова М.М., Мухин П.Н. Секреторная функция контралатеральных околоушных желёз. Казанский медицинский журнал. 2022;103(6):1034–1039. DOI: 10.17816/KMJ112128.

[3] Pestova VN, Zaitseva EA. Saliva collection methods to account for salivation asymmetry in right-handed and left-handed people. Vyatskiy meditsinkiy vestnik. 2009;(1):115–116. (In Russ.)

[4] Пестова В.Н., Зайцева Е.А. Методы сбора слюны для учёта асимметрии саливации у правшей и левшей. Вятский медицинский вестник. 2009;(1):115–116. EDN: OXUVUL.

[5] Kandyba DV. Stroke. Russian Family Doctor. 2016;20(3):5–15. (In Russ.) DOI: 10.17816/RFD201635-15.

[6] Кандыба Д.В. Инсульт. Российский семейный врач. 2016;20(3):5–15. DOI: 10.17816/RFD201635-15.

[7] Bondarenko IA, Chesnakova TV. Situs viscerus inversus totalis (clinical case). Radiology — practice. 2014;(2):57–63. (In Russ.)

[8] Бондаренко И.А., Чеснакова Т.В. Полная транспозиция органов (клинический случай). Радиология — практика. 2014;(2):57–63. EDN: SCFDUL.

[9] Kasimova RM, Timoshok AD. Situs viscerus inversus totalis (clinical case). Scientific review. Pedagogical sciences. 2019;(5-3):69–74. (In Russ.)

[10] Касимова Р.М., Тимошок А.Д. Полная транспозиция органов (клинический случай). Научное обозрение. Педагогические науки. 2019;(5-3):69–74.

[11] Tsimmernam YaS, Dimov AS. Scientific legacy of I.V. Davydovsky — philosophical foundations of general pathology. Clinical Medicine. 2016;(8):565–574. (In Russ.) DOI: 10.18821/0023-2149-2016-94-8-565-574.

[12] Циммерман Я.С., Димов А.С. Научное наследие И.В. Давыдовского: философские основы общей патологии. Клиническая медицина. 2016;(8):565–574. DOI: 10.18821/0023-2149-2016-94-8-565-574.

[13] Romacheva IF, Yudin LA, Afanasyev VV, Morozov AN. Zabolevaniya i povrezhdeniya slyunnykh zhelyoz. (Diseases and injuries of the salivary glands.) M.: Meditsina; 1987. 238 р. (In Russ.)

[14] Ромачева И.Ф., Юдин Л.А., Афанасьев В.В., Морозов А.Н. Заболевания и повреждения слюнных желёз. М.: Медицина; 1987. 238 с.

[15] Afanasyev VV, Mirzakulova UR. Slyunnye zhelezy. Bolezni i travmy. Rukovodstvo dlya vrachey. (Salivary glands. Diseases and injuries. A guide for doctors.) M.: GEOTAR-Media; 2019. 315 р. (In Russ.)

[16] Афанасьев В.В., Мирзакулова У.Р. Слюнные железы. Болезни и травмы. Руководство для врачей. М.: ГЭОТАР-Медиа; 2019: 315 с.

[17] Höhmann D, Landwehr P. Clinical value of sialography in digital and conventional imaging technique. HNO. 1991;39(1):13–17. (In Germ.) PMID: 2030081.

[18] Tshipskiy AV, Kondrashin SA. Contrast radiography of the salivary glands. Stomatologiya. 2015;94(6):45–49. (In Russ.) DOI: 10.17116/stomat201594645-49.

[19] Щипский А.В., Кондрашин С.А. Контрастная рентгенография слюнных желёз. Стоматология. 2015;94(6):45–49. DOI: 10.17116/stomat201594645-49.

[20] Borkovic Z, Peric B, Ozegovic I. The value of digital subtraction sialography in the diagnosis of diseases of the salivary glands Acta Stomat Croat. 2002;36(4):505–506.

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