On the hemostatic effect of blood transfusion in hemophilia

Abstract

Blood transfusion is widely used for various types of bleeding, as well as hemorrhagic diathesis and hemophilia, as one of the forms of this diathesis. Most authors are unanimous in their view that one of the main causes of hemophilia is congenital decreased blood clotting, which depends on a lack of thrombin and thrombokinase. Sali believes that in hemophiliacs, the vascular endothelium and blood cells suffer from functional insufficiency in the sense of producing substances necessary for blood clotting. Others believe that the cause of hemophilia is the thinness and fragility of the vascular wall, making it brittle and unable to contract. Oppel suggests that hemophiliacs suffer from congenital hypofunction of the liver in terms of the production of proserosine, the participation of which is necessary for blood clotting.

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