On the priority of V.S. Gruzdev in the experiment on in vitro fertilization

Abstract

Among the many methods of teaching students, special attention is drawn to “becoming a specialist through the implementation of scientific research”. V.S. Gruzdev, having mastered under the guidance of Professor V.A. Manassein the first skills of scientific research, widely used them in his development as an obstetrician-gynecologist. Later he formed his own scientific school, which still exists today. One of his early works was the study of artificial insemination in mammals. This research, ahead of its time, marked the beginning of the study of in vitro fertilization. He revealed an important regularity in the development of a fertilized egg when it is planted in the oviduct. Other contemporary embryologists also spoke about this feature, mentioning that V.S. Gruzdev became the first scientist who described it. It is important that Viktorin Sergeevich proposed a plan to resolve the problem of infertile marriage, through his experiments — as a result of his research, followers were able to significantly increase the number of pregnancies that occurred as a result of the treatment of obstruction of the fallopian tubes and identify problems associated with the pathology of spermatogenesis in men, and their role in an infertile marriage. Professor P.V. Manenkov, being a student and follower of V.S. Gruzdev, continued the work of his teacher and was also able to further participate in the development of a bill draft on heteronomous conception.

Keywords

infertility / artificial insemination / egg / follicle / ovulation / V.S. Gruzdev / P.V. Manenkov

References

[1] Gruzdev VS. Experiments with artificial insemination of mammalian eggs. Vrach. 1897;(42):1199. (In Russ.)

[2] Груздев В.С. Опыты с искусственным оплодотворением яиц млекопитающих. Врач. 1897;(42):1199.

[3] Gruzdev VS. Kurs akusherstva i zhenskikh bolezney. M.: Narodnyy komissariat zdravookhraneniya; 1919. Chast' 1. Anatomiya i fiziologiya zhenskogo polovogo apparata. 100 р. (In Russ.)

[4] Груздев В.С. Курс акушерства и женских болезней. М.: Народный комиссариат здравоохранения; 1919. Часть 1. Анатомия и физиология женского полового аппарата. 100 с.

[5] Kakushkin NM. V.S. Gruzdev — Experiments with artificial insemination of mammalian eggs. (Vrach. 1897 g. №42, s. 1199.) Zhurnal akusherstva i zhenskikh bolezney. 1898;12(9):1087–1088. (In Russ.)

[6] Какушкин Н.М. В.С. Груздев. Опыты с искусственным оплодотворением яиц млекопитающих. (Врач. 1897 г. №42, с. 1199.) Журнал акушерства и женских болезней. 1898;12(9):1087–1088.

[7] Gruzdev VS. Reviews of the most important works in obstetrics and gynecology for 1897. Russkiy arkhiv patologii, klinicheskoy meditsiny i bakteriologii. 1899;VІІ(3–4):93. (In Russ.)

[8] Груздев В.С. Обзоры важнейших работ по акушерству и гинекологии за 1897 г. Русский архив патологии, клинической медицины и бактериологии. 1899;VІІ(3–4):93.

[9] Krasovskaya OV, Diomidova NA. Fertilization of rabbit eggs in vitro. Biologicheskiy zhurnal. 1934;13(2):327–342. (In Russ.)

[10] Красовская О.В., Диомидова Н.А. Оплодотворение яиц кролика in vitro. Биологический журнал. 1934;13(2):327–342.

[11] Serebrovskiy AA. Gibridizatsiya zhivotnykh. (Hybridization of animals.) M.-L.: Biomedigiz; 1935. 397 р. (In Russ.)

[12] Серебровский А.А. Гибридизация животных. М.-Л.: Биомедгиз; 1935. 397 с.

[13] Petrov GN. Protsess oplodotvoreniya vne organizma yaytsekletok nekotorykh mlekopitayushchikh zhivotnykh i cheloveka. Dis. … kand. med. nauk. (The process of fertilization outside the body of the eggs of some mammals and humans. Dissertation of the candidate of medical sciences.) Simferopol: [n.p.] ;1959. 14 p. (In Russ.)

[14] Петров Г.Н. Процесс оплодотворения вне организма яйцеклеток некоторых млекопитающих животных и человека. Дис. … канд. мед. наук. Симферополь: [б.и.]; 1959. 14 с.

[15] Litvinov VV, Rybalka AN, Sulima AN. Ternistyy put' k priznaniyu, ili chetyre rozy… vmesto Nobelevskoy premii. 2-e izdanie. (A thorny path to recognition, or four roses ... instead of the Nobel Prize. 2nd edition.) M.: Litterra; 2020. 239 p. (In Russ.)

[16] Литвинов В.В., Рыбалка А.Н., Сулима А.Н. Тернистый путь к признанию, или четыре розы… вместо Нобелевской премии. 2-е издание. М.: Литтерра; 2020. 239 с.

[17] Nikitin AI. Already history... Problemy reproduktsii. 1997;3(3):7–12. (In Russ.)

[18] Никитин А.И. Уже история... Проблемы репродукции. 1997;3(3):7–12.

[19] Kitaev EM. Iz istorii razvitiya programmy EKO v Rossii. (From the history of the development of the IVF program in Russia.) M.: Svitchayld-Media; 2007. 86 р. (In Russ.)

[20] Китаев Э.М. Из истории развития программы ЭКО в России. М.: Свитчайлд-Медиа; 2007. 86 с.

[21] Manenkov PV. VS Gruzdev. M.: Medgiz; 1952. 136 р. (In Russ.)

[22] Маненков П.В. В.С. Груздев. М.: Медгиз; 1952. 136 с.

[23] Kozlov LA. Professor Pavel Vasil'evich Manenkov. Kazan': MedDoc; 2022. 376 р. (In Russ.)

[24] Козлов Л.А. Профессор Павел Васильевич Маненков. Казань: МеДДок; 2022. 376 с.

[25] Manenkov PV. On heteronomous conception (letter to the editor). Kazan Medical Journal. 1970;(1):90. (In Russ.)

[26] Маненков П.В. О гетерономном зачатии (письмо в редакцию). Казанский медицинский журнал. 1970;(1):90.

RIGHTS & PERMISSIONS

Eco-Vector