Lipid criterion of hardness as an auxiliary parameter during investigation of the lens nucleus in cataract patients

Abstract

Aim. To identify the lipid markers of changes in the mechanical characteristics of the lens nucleus on the example of sulfur gland secretions of the ear canal. Methods. Examined were 50 patients aged from 52 to 83 years with cataracts of varying degrees of maturity. Studied was the composition of the higher fatty acids of the lens nucleus and of the earwax in patients. The evaluation of lens nucleus hardness was performed on an original device. Results. Palmitic acid, stearic acid and polyunsaturated fatty acids were dominant in the earwax, less was the content of lauric and linolenic acids. Revealed was a strong correlation between the content of polyunsaturated fatty acids in the earwax and the hardness of the lens. Developed was a method for predicting the hardness of the lens nucleus and for evaluating lipid metabolism in the lens. Conclusion. Lipid composition of the earwax may serve as an auxiliary parameter for determining the hardness of the lens nucleus and for justification of the choice of lens phacoemulsification method.

Keywords

hardness of the lens / polyunsaturated higher fatty acids / earwax / lipid criterion of hardness

References

[1] Веселовская З.Ф. Катаракта. - Киев: Книга плюс, 2002. - 208 с.

[2] Коростелёва Н.Ф., Марченкова Т.Е. Значение биомикроскопии в определении плотности катаракты перед факоэмульсификацией // Вест. офтальм. - 1989. - №6. - С. 43-45.

[3] Коростелёва Н.Ф., Нерсесов Ю.Э. Метод определения твёрдости ядра хрусталика // Офтальмохирургия. - 1990. - №1. - С. 42-45.

[4] Kisic B., Miric D., Zoric L. et al. Role of lipid peroxidatoin in pathogenesis of senile cataract // Vojnosanit. Pregl. - 2009. - Vol. 66. - Р. 371-375.

[5] Mirsamadi M., Nourmohammadi I. Correlation of human age-related cataract with some blood biochemistry constituens // Ophthalm. Res. - 2003 - Vol. 35. - Р. 329-334.

RIGHTS & PERMISSIONS

Chuprov A.D., Kudryavtseva J.V.