Laser technologies in the management of patients with complicated forms of sexually transmitted infections

Abstract

Aim. To study and assess the clinical effectiveness of medical laser technologies in the complex treatment of complicated forms of sexually transmitted infections (STIs).

Methods. Modern technologies of molecular biological laboratory diagnostics in real time with Real-time amplifier CFX96 Bio-Rad Laboratorias (USA), were used for etiological diagnostics of pathogens. Determination of infectious and inflammatory lesions of tissues of the genital system was carried out using ultrasound on ALOKA CCL-680 device (Japan) using cavity sensors with an operating frequency of 5 MHz. Drug therapy was carried out in accordance with the Federal clinical recommendations of the Russian society of dermatovenerologists and cosmetologists “Dermatovenerology” (Moscow, 2015). To assess the effectiveness of laser technologies in complex treatment, patients with complicated forms of STIs were randomly divided into 2 groups: the control group (32 patients), where only traditional therapy was used, and the main group (108 patients), in which, in addition to traditional therapy, treatment was supplemented with laser therapy.

Results. The effectiveness of antibiotic therapy in the main group was 14.0%, and treatment using laser technology was 33.1% higher than the effectiveness of treatment in the control group. This shows the effectiveness of laser technologies in the treatment of infectious and inflammatory structural changes in the tissues of the organs of the reproductive system.

Conclusion. The use of medical laser technologies in the treatment of complicated forms of STIs with a change in exposure parameters depending on the revealed inflammatory-structural changes in the tissues of the affected organs showed high efficiency (79.6%); this technology can be recommended for use in practical health care for the treatment of complicated forms of STIs.

Keywords

complicated forms of sexually transmitted infections (STIs) / laser technology / evaluation of treatment effectiveness

References

[1] Kubanova A.A., Melekhina P.E., Kubanov A.A. Key objectives of dermatovenerological assistance to the Russian Federation population for the period up to 2024. Results of the activities of medical organizations in providing dermatovenerological assistance to the Russian Federation population in 2017. Vestnik dermatologii i venerologii. 2018; 94 (5): 9–25. (In Russ.) DOI: 10.25208/0042-4609-2018-94-5-9-25.

[2] Кубанова А.А., Мелехина П.Е., Кубанов А.А. Основные задачи развития дерматовенерологической помощи населению Российской Федерации на период до 2024 года. Результаты деятельности медицинских организаций по оказанию дерматовенерологической помощи населению Российской Федерации в 2017 году. Вестн. дерматол. и венерол. 2018; 94 (5): 9–25. DOI: 10.25208/0042-4609-2018-94-5-9-25.

[3] Letyaeva O.I., Gizinger O.A. The unsolved problems of therapy of inflammatory diseases of the female sex organs in the reproductive age. 2012; (6): 12–18. (In Russ.)

[4] Летяева О.И., Гизингер О.А. Нерешённые вопросы терапии воспалительных заболеваний женских половых органов в репродуктивном возрасте. Вопр. гинекол., акушерства и перинатол. 2012; (6): 12–18.

[5] Kuzʹmin V.N. Mo­dern approaches in the treatment of pelvic inflammatory di­seases in women. Consil. med. 2009; 11 (6): 21–23. (In Russ.)

[6] Кузьмин В.Н. Современные подходы в лечении воспалительных заболеваний органов малого таза у женщин. Consil. med. 2009; 11 (6): 21–23.

[7] Krasnopolsky V.I., Serova O.F., Tumanova V.A. et al. Impact of infections on the female reproductive system. Rossiyskiy vestnik akusherstva i ginekologii. 2004; (5): 26–29. (In Russ.)

[8] Краснопольский В.И., Серова О.Ф., Туманова В.А. и др. Влияние инфекций на репродуктивную систему женщин. Рос. вестн. акушерства и гинекол. 2004; (5): 26–29.

[9] Ryumin D.V., Savelyeva E.M. Features of the immune status of patients with mixed urogenital infections and possibilities of its correction. Prakticheskaya meditsina. 2013; (1–4): 42–45. (In Russ.)

[10] Рюмин Д.В., Савельева Е.М. Особенности иммунного статуса у больных смешанными урогенитальными инфекциями и возможности его коррекции. Практич. мед. 2013; (1–4): 42–45.

[11] Perlamutrov Yu.N., Chernova N.I. The potential of improving the treatment of bacterial and viral urogenital infections. Klinicheskaya dermatologiya i ve­nerologiya. 2016; 15 (1): 28–33. (In Russ.) DOI: 10.17116/klinderma201615128-33.

[12] Перламутров Ю.Н., Чернова Н.И. Возможности совершенствования терапии урогенитальной бактериально-вирусной инфекции. Клин. дерматол. и венерол. 2016; 15 (1): 28–33. DOI: 10.17116/klinderma201615128-33.

[13] Abdrakh­manov R.M., Petrova A.S., Abdrakhmanov A.R. Clinical and laboratory assessment of the role of opportunistic pathogenic sexually transmitted flora in the formation of pathological conditions of cervix and cervical canal in women of reproductive age. Sovremennye problemy nauki iobrazovaniya. 2018; (1): 72. http://www.science-education.ru/ru/article/view?id=27413 (access date: 27.11.2019). (In Russ.)

[14] Абдрахманов Р.М., Петрова А.С., Абдрахманов А.Р. Клинико-лабораторная оценка роли условно-патогенной флоры, передаваемой половым путём, в формировании патологических состояний шейки матки и цервикального канала у женщин репродуктивного возраста. Соврем. пробл. науки и образования. 2018; (1): 72. http://www.science-education.ru/ru/article/view?id=27413 (дата обращения: 27.11.2019).

[15] Fedorova V.A., Sultanakhmedov Eh.S., Saltykov Yu.V. et al. Improvement of laboratory diagnostics of urogenital chlamydial infection in patients with impaired reproductive functions found to be infected with Chlamydia trachomatis. Vestnik dermatologii i venerologii. 2017; (2): 34–44. (In Russ.) DOI: 10.25208/0042-4609-2017-93-2-34-44.

[16] Фёдорова В.А., Султанахмедов Э.С., Салтыков Ю.В. и др. Совершенствование лабораторной диагностики урогенитальной хламидийной инфекции у пациентов с нарушением репродуктивной системы, инфицированных Chlamydia trachomatis. Вестн. дерматол. и венерол. 2017; (2): 34–44. DOI: 10.25208/0042-4609-2017-93-2-34-44.

[17] Prilepskaya V.N. Vospalitelʹnye zabolevaniya organov malogo taza. (Pelvic inflammatory disease.) M: ­GEOTAR-Media. 2010; 128 p. (In Russ.)

[18] Прилепская В.Н. Воспалительные заболевания органов малого таза. М: ГЭОТАР-Медиа. 2010; 128 с.

[19] Prileps­kaya V.N. Infektsii, peredayushchiesya polovym putem. Klinicheskie lektsii. (Sexually transmitted infections. Cli­nical lectures.) Ed. by V.N. Prilepskoy. M: GEOTAR-­Media. 2014; 160 p. (In Russ.)

[20] Прилепская В.Н. Инфекции, передающиеся половым путём. Клинические лекции. Под ред. В.Н. Прилепской. М.: ГЭОТАР-Медиа. 2014; 160 с.

[21] Materials of XVIII FIGO Congress of Gynecology and Obstetrics. Kuala Lumpur Malaysia. 5–10 Nov. 2006; 45 р.

[22] Federalʹnye klinicheskie rekomendatsii. Dermatovenerologiya 2015. Bolezni kozhi. Infektsii, peredavaemye polovym putem. 5-e izd., pererab. i dop. (Federal clinical recommendations of the Russian society of dermatovenerologists and cosmetologists “Dermatovenerology”, 5 ed.) M.: Delovoy ehkspress. 2016; 768 р. (In Russ.)

[23] Федеральные клинические рекомендации. Дерматовенерология 2015. Болезни кожи. Инфекции, передаваемые половым путём. 5-е изд., перераб. и доп. М.: Деловой экспресс. 2016; 768 с.

[24] Kheyfets Yu.B. Metodicheskie rekomendatsii po primene­niyu apparata kvantovoy terapii «MILTA». (Guidelines for the use of the quantum therapy apparatus “MILTA”.) М.: ZAО “MILTA-PKP GIT”. 2014; 275 р. (In Russ.)

[25] Хейфец Ю.Б. Методические рекомендации по применению аппарата квантовой терапии «МИЛТА». М.: ЗАО «МИЛТА-ПКП ГИТ». 2014; 275 с.

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Misbakhova A.G., Abdrakhmanov A.R., Belyaev A.R.