Some approaches to dispanserization of patients with hypertensive disease at territorial internist's area

Abstract

Aim. To study creatinine clearance, body mass index and to perform ROSE survey amomg patients with hypertension of different age groups at territorial internist's area.

Methods. The study involved 112 patients aged 40 to 75 years. Patients were divided into two groups according to the age: group 1 — 40 to 61 years, 55 people (15 men and 40 women), the average age 52.6±7.1 years; group 2 — 62 to 75 years, 57 people (15 men and 42 women), the average age 69.8±4.4 years. Creatinine clearance and body mass index were measured, and ROSE survey was conducted.

Results. In group 1 creatinine clearance <60 ml/min was in 5 (9%) subjects, in group 2 — in 20 (35%; p=0.002). In group 1 15 (27%) subjects had normal body mass, in group 2 — 5 (9%). In group 1 overweight was registered in 18 (33%) subjects, and in group 2 — in 24 (42%; p=0.407). Class I obesity in group 1 was found in 15 (27%) patients, in group 2 — in 16 (28%; p=0.907). Class II obesity in group 1 was noted in 5 (9%) patients, in group 2 — in 4 (7%; p=0.955). Class III obesity in group 1 was registered in 2 (4%) people and in 8 (14%) in group 2 (p=0.110). According to the results of ROSE questionnaire, signs of angina pectoris were found in 7 (13%) patients in group 1 and 17 (30%) in group 2 (p=0.048).

Conclusion. In the territorial internist's area the proportion of cases of overweight and obesity among patients of groups 1 and 2 with hypertension did not differ significantly (p >0.05); in patients from group 2 with hypertension creatinine clearance less than 60 ml/min was identified 3.9 times more often than in the younger age group (p=0.002); in patients of group 2 with hypertension were 2.3 times more likely to have angina, according to ROSE questionnaire than in group 1 (p=0.048).

Keywords

hypertension / angina / obesity / creatinine clearance

References

[1] Kuranov A.A., Baleev M.S., Mitrofanova N.N. et al. Some aspects of the pathogenesis of atherosclerosis and risk factors for cardiovascular disease. Fundamental'nye issledovaniya. 2014; 10 (6): 1234–1238. (In Russ.)

[2] Куранов А.А., Балеев М.С., Митрофанова Н.Н. и др. Некоторые аспекты патогенеза атеросклероза и факторы риска развития сердечно-сосудистых заболеваний. Фундаментал. исслед. 2014; 10 (6): 1234–1238.

[3] Murom­tseva G.A., Kontsevaya A.V., Konstantinov V.V. et al. The prevalence of non-infectious diseases risk factors in Russian population in 2012–2013 . The results of ECVD-RF. Kardiovaskulyarnaya terapiya i profilaktika. 2014; 13 (6): 4–11. (In Russ.)

[4] Муромцева Г.А., Концевая А.В., Константинов В.В. и др. Распространённость факторов риска неинфекционных заболеваний в российской популяции в 2012–2013 гг. Результаты исследования ЭССЕ-РФ. Кардиоваск. терап. и профил. 2014; 13 (6): 4–11. DOI: 10.15829/1728-8800-2014-6-4-11.

[5] Chazova I.E., Zhernakova Yu.V. On behalf of the experts. Clinical guidelines. Diagnosis and treatment of arterial hypertension. Systemnye gipertensii. 2019; 16 (1): 6–31. (In Russ.)

[6] Чазова И.Е., Жернакова Ю.В. (от имени экспертов). Клинические рекомендации. Диагностика и лечение артериальной гипертонии. Системные гипертензии. 2019; 16 (1): 6–31. DOI: 10.26442/2075082x.2019.1.190179.

[7] Iskenderov B.G., Sisina O.N., Mamedov M.N. The risk of acute kidney injury and its progno­stic value in patients with various glomerular filtration rates, underwent aortocoronary bypass grafting. Kardiovasku­lyarnaya terapiya i profilaktika. 2015; 14 (3): 54–59. (In Russ.)

[8] Искендеров Б.Г., Сисина О.Н., Мамедов М.Н. Риск развития острого повреждения почек и его прогностическое значение у больных с различной скоростью клубочковой фильтрации, подвергшихся аортокоронарному шунтированию. Кардиоваскуляр. терап. и профил. 2015; 14 (3): 54–59. DOI: 10.15829/1728-8800-2015-3-54-59.

[9] Montalescot G., Sechtem U., Achenbach S. et al. 2013 ESC guidelines on the management of stable coronary artery disease. Rossiyskiy kardiologicheskiy zhurnal. 2014; 19 (7): 7–79. (In Russ.)

[10] Montalescot G., Sechtem U., Achenbach S. et al. Рекомендации по лечению стабильной ишемической болезни сердца. ESC 2013. Рос. кардиол. ж. 2014; 19 (7): 7–79.

[11] On approval of the procedure for preventive medical examination and medical examination of certain groups of the adult population. Order of the Ministry of health of Russia of 13.03.2009 №124n. (In Russ.)

[12] Об утверждении порядка проведения профилактического медицинского осмотра и диспансеризации определённых групп взрослого населения. Приказ Мин­здрава России от 13.03.2019 №124н.

[13] Baturin A.K., Sorokina E.Ju., Pogozheva A.V. et al. A study of regional differences of gene polymorphisms of obesity in the population of Russia. Voprosy pitaniya. 2014; 83 (S3): 270. (In Russ.)

[14] Батурин А.К., Сорокина Е.Ю., Погожева А.В. и др. Изучение региональных особенностей полиморфизма генов ожирения у населения России. Вопр. питания. 2014; 83 (S3): 270.

[15] Babkin A.P., Romanova M.M. Psychological status, actual food, gustatory sensitivity as risk factors of syndrome of dyspepsia and obesity. Vestnik novykh meditsinskikh tekhnologiy. 2013; 20 (2): 204–208. (In Russ.)

[16] Бабкин А.П., Романова М.М. Психологический статус, фактическое питание, вкусовая чувствительность как факторы риска синдрома диспепсии и ожирения. Вестн. новых мед. технол. 2013; 20 (2): 204–208.

[17] On approval of the recommendations on rational norms of consumption of foods meeting mo­dern requirements of healthy eating. Order of the Ministry of health of the Russian Federation from August 19, 2016 No. 614. (In Russ.)

[18] Об утверждении Рекомендаций по рациональным нормам потребления пищевых продуктов, отвечающих современным требованиям здорового питания. Приказ Министерства здравоохранения РФ от 19 августа 2016 г. №614.

[19] Trukhacheva N.V. Matematicheskaya statistika v mediko-biologicheskikh issledovaniyakh s primeneniem paketa STATISTICA. (Mathematical statistics in biomedical research with the use of STATISTICA.) Moscow: ­GEOTAR-Media. 2012; 379 р. (In Russ.)

[20] Трухачева Н.В. Математическая статистика в медико-биологических исследованиях с применением пакета STATISTICA. М.: ГЭОТАР-Медиа. 2012; 379 с.

[21] Borovikov V.P. Populyarnoe vvedenie v sovremennyy analiz dannykh v sisteme STATISTICA. (A popular introduction to modern data analysis in STATISTICA system.) Moscow. 2013; 288 р. (In Russ.)

[22] Боровиков В.П. Популярное введение в современный анализ данных в системе STATISTICA. М. 2013; 288 с.

RIGHTS & PERMISSIONS

Babushkin I.E., Gataulina O.V., Demina E.I., Bublikov D.S., Duruda N.V., Kudeyarova T.V.