Esophageal-gastrointestinal-diaphragmatic murmur - a new objective sign of diaphragmatic hernias
A A Garanin , A M Osadchuk , E E Adyshirin-Zade
Kazan medical journal ›› 2019, Vol. 100 ›› Issue (2) : 327 -332.
Esophageal-gastrointestinal-diaphragmatic murmur - a new objective sign of diaphragmatic hernias
Aim. To present a description and scientific substantiation of a new objective sign in patients with hiatal hernias.
Methods. The study included 127 patients with diaphragmatic hernia, who made up the group of patients, including 65 women and 62 men, mean age 56.2±11.4 years. The control group was represented by the results of a survey of 100 practically healthy people: 55 women and 45 men, the average age of 52.6±2.3 years. All patients included in the study group, underwent upper endoscopy and fluoroscopy of the esophagus and stomach with a suspension of barium sulfate, the results of which were compared with the data of auscultation of the chest.
Results. The description and scientific substantiation of the physical sign of diaphragmatic hernias was presented, which is pathological peristalsis at four points of auscultation on the thorax. The factors that led to the choice of localization of the points at which auscultation of esophageal-gastrointestinal-diaphragmatic murmur is carried out in this pathology, are presented. Pathophysiological mechanisms causing the appearance of pathological peristalsis of the esophagus and stomach, which is the essence of the proposed symptom of hiatal hernia, were found and substantiated. Sensitivity and specificity of a new method of detecting diaphragmatic hernia were calculated, the positive and negative predictive values were determined. High efficiency of auscultation of abnormal motility as a diagnostic method was demonstrated. The frequency of clinical symptoms in patients with hiatal hernia and their comparison with the world experience of observation of patients with this pathology are shown.
Conclusion. The proposed objective sign, which has a very high sensitivity and specificity, is an attempt to fill the currently existing «diagnostic gap» between the subjective sensations of a patient with diaphragmatic hernia and instrumental diagnostic methods that have certain limitations in application.
hiatal hernia / pathological peristalsis / esophageal-gastric-diaphragmatic murmur / physical method of diagnosis
| [1] |
Fujiwara Y., Arakawa T. Epidemiology and clinical characteristics of GERD in the Japanese population. J. Gastroenterol. 2009; 44 (6): 518–534. DOI: 10.1007/s00535-009-0047-5. |
| [2] |
Fujiwara Y., Arakawa T. Epidemiology and clinical characteristics of GERD in the Japanese population. J. Gastroenterol. 2009; 44 (6): 518-534. DOI: 10.1007/s00535- 009-0047-5. |
| [3] |
Ivashkin V.T., Maev I.V., Trukhmanov A.S. et al. Diagnostics and treatment of gastroesophageal reflux disease: clinical guidelines of the Russian gastroenterological association. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2017; 27 (4): 75–95. (In Russ.) |
| [4] |
Ивашкин В.Т., Маев И.В., Трухманов А.С. и др. Клинические рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению гастроэзофагеальной рефлюксной болезни. Рос. ж. гастроэнтерол., гепатол., колопроктол. 2017; 27 (4): 75-95. |
| [5] |
Lis M.A., Solonenko Ju.T., Sokolov K.N. Propedevtika vnutrennikh bolezney. (Propaedeutics of internal diseases.) Ed. 4. Grodno; Izd-vo Grevtsova. 2013; 495 p. (In Russ.) |
| [6] |
Лис М.А., Солоненко Ю.Т., Соколов К.Н. Пропедевтика внутренних болезней. 4-е изд. Гродно: Изд-во Гревцова. 2013; 495 с. |
| [7] |
Rodin A.G., Bazaev A.V., Nikitenko A.I. Surgical treatment of hiatal hernia of elderly patients. Meditsinskiy al'manakh. 2014; 3 (33): 117–120. (In Russ.) |
| [8] |
Родин А.Г., Базаев А.В., Никитенко А.И. Хирургическое лечение грыж пищеводного отверстия диафрагмы у больных пожилого возраста. Мед. альманах. 2014; 3 (33): 117-120. |
| [9] |
Sobrino-Cossíoa S., Soto-Pérez J.C., Coss-Adamee E. et al. Síntomas y complicaciones posfunduplicatura: abordaje diagnóstico y tratamiento. Revista de Gastroenterologia de Mexico. 2017; 82 (3): 234–247. DOI: 10.1016/ |
| [10] |
Sobrino-Cossíoa S., Soto-Pérez J.C., Coss-Adamee E. et al. Síntomas y complicaciones posfunduplicatura: abordaje diagnóstico y tratamiento. Revista de Gastroenterologia de Mexico. 2017; 82 (3): 234-247. DOI: 10.1016/ j.rgmx.2016.08.005. |
| [11] |
j.rgmx.2016.08.005. |
| [12] |
Тумаренко А.В., Скворцов В.В. Грыжа пищеводного отверстия диафрагмы в практике терапевта. Крымский терап. ж. 2015; 4: 80-84. |
| [13] |
Tumarenko A.V., Skvortsov V.V. Hernia of the esophageal opening of the diaphragm in the practice of the therapist. Krymskiy terapevticheskiy zhurnal. 2015: 4; 80–84. (In Russ.) |
| [14] |
Пучков К.В., Филимонов В.Б. Грыжи пищеводного отверстия диафрагмы. М.: Медпрактика-М. 2003; 172 с. |
| [15] |
Puchkov K.V., Filimonov V.B. Gryzhi pishchevodnogo otverstiya diafragmy. (Hiatal hernia (HH) in therapeautic practice.) Moscow: Medpraktika-M. 2003; 172 р. (In Russ.) |
| [16] |
Roman S., Kahrilas P.J. The diagnosis and management of hiatus hernia. BMJ. 2014; 349: g6154. DOI: 10.1136/bmj.g6154. |
| [17] |
Roman S., Kahrilas P.J. The diagnosis and management of hiatus hernia. BMJ. 2014; 349: g6154. DOI: 10.1136/bmj.g6154. |
| [18] |
Осадчук М.А., Осадчук М.М. Синдром перекрёста функциональной диспепсии, гастроэзофагеальной рефлюксной болезни и синдрома раздражённого кишечника: оптимизация терапии. Русский мед. ж. 2015; (28): 1690-1692. |
| [19] |
Osadchuk M.A., Osadchuk M.M. Cross-cycle syndrome of functional disposition, gastroesophageal reflux disease and irritable intelligence syndrome: optimization of therapy. Russkiy meditsinskiy zhurnal. 2015; (28): 1690–1692. (In Russ.) |
| [20] |
Левин М.Д., Мендельсон Г. Кольцо Шацкого как симптом гастроэзофагеальной рефлюксной болезни. Вестн. рентгенол. и радиол. 2015; (1): 5-15. DOI: 10.20862/0042-4676-2015-0-1-5-15. |
| [21] |
Levin M.D., Mendel'son G. Schatzki ring as a symptom of gastroesophageal reflux disease. Vestnik rentgenologii i radiologii. 2015; (1): 5–15. (In Russ.) |
| [22] |
Сторонова О.А., Трухманов А.С., Джахая Н.Л., Ивашкин В.Т. Нарушения пищеводного клиренса при гастроэзофагеальной рефлюксной болезни и возможности их коррекции. Рос. ж. гастроэнтерол., гепатол., колопроктол. 2012; 2: 14-21. |
| [23] |
Storonova O.A., Trukhmanov A.S., Dzhakhaya N.L., Ivashkin V.T. Disorders of esophageal clearance in gastroesophageal reflux disease and the possibility of their correction. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2012; 2: 14–21. (In Russ.) |
| [24] |
Киреева К.В., Канькова Н.Ю., Шабунина Е.И. и др. Изменение содержания производных оксида азота у детей с воспалительными заболеваниями пищевода и желудка. Мед. альманах. 2015; (4): 118-121. |
| [25] |
Kireeva K.V., Kan'kova N.Yu., Shabunina E.I. et al. Change in the content of nitric oxide derivatives in children with inflammatory diseases of the esophagus and stomach. Meditsinskiy al'manakh. 2015; (4): 118–121. (In Russ.) |
| [26] |
Majka J., Wierdak M., Brzozowska I. et al. Melatonin in prevention of the sequence from reflux esophagitis to Barrett’s esophagus and esophageal adenocarcinoma: Experimental and clinical perspectives. Int. J. Mol. Sci. 2018; 19: 2033. DOI: 10.3390/ijms19072033. |
| [27] |
Majka J., Wierdak M., Brzozowska I. et al. Melatonin in prevention of the sequence from reflux esophagitis to Barrett’s esophagus and esophageal adenocarcinoma: Experimental and clinical perspectives. Int. J. Mol. Sci. 2018; 19: 2033. DOI: 10.3390/ijms19072033. |
| [28] |
Гаранин А.А. Физикальный способ диагностики грыж пищеводного отверстия диафрагмы. Патент на изобретение РФ №2655440. Бюлл. от 28.05.2018. |
| [29] |
Garanin A.A. Physical method of diagnosis of hiatal hernias. Patent for invention RF №2655440. Bulletin issued on 28.05.2018. (In Russ.) |
Garanin A.A., Osadchuk A.M., Adyshirin-Zade E.E.
/
| 〈 |
|
〉 |