Role of genus Candida in etiology of nosocomial infections in a multidisciplinary surgical clinic

Abstract

Aim. To establish the role of genus Candida in etiology of nosocomial infections in a multidisciplinary surgical clinic of Azerbaijan Medical University in 2014-2016.

Methods. Microbiological study was performed on the pathological material from 41 patients with nosocomial pneumonia, 40 patients with surgical site infections and 46 patients with nosocomial sepsis.

Results. Nosocomial infections developing in a multidisciplinary surgical clinic were found to depend on localization of nosocomial infections. In nosocomial pneumonia 24% of all isolated microorgamisms were fungi of genus Candida among which C. albicans was prevailing: 9 of 12 isolated strains of Candida (75%) were identified as C. albicans. In patients with surgical site infections 10.7% of all isolated microorganisms were fungi of the genus Candida among which C. albicans was also prevailing: 4 of 6 isolated strains of Candida (66.7%) were identified as C. albicans. The isolated strains of Candida were sensitive to the studied antifungal medicines (amphotericin B, fluconazole, voriconazole, ketokonazole, nystatin).

Conclusion. In nosocomial infection and surgical site infections Candida fungi constituted 10.7-24% of all microorganisms isolated from the patients; the isolated Candida fungi - causative agents of nosocomial infections - were not resistant to antifungal medicines (amphotericin B, fluconazole, voriconazole, ketokonazole, nystatin).

Keywords

nosocomial infections / microorganisms / fungi of genus Candida / sensitivity to antifungal medicines

RIGHTS & PERMISSIONS

Atakishizade S.A.