Clinical and functional characteristics of patients with colorectal cancer complicated by acute intestinal obstruction
F Sh Akhmetzyanov , A K Saetgaraev , A V Pasheev , N A Valiev , M V Levin , I V Shaymardanov , K K Sadykov
Kazan medical journal ›› 2018, Vol. 99 ›› Issue (6) : 869 -875.
Clinical and functional characteristics of patients with colorectal cancer complicated by acute intestinal obstruction
Aim. To study the clinical and functional features of patients with colorectal cancer complicated by acute intestinal obstruction.
Methods. A retrospective analysis of the data of 147 patients with colorectal cancer operated on from 2014 to 2016 for urgent indications for acute intestinal obstruction was performed. The study of lethality during the period from 1993 to 2016 was carried out separately. The study was performed in the clinic of urgent oncologic surgery of the State Autonomous Healthcare Institution “Republican Clinical Oncologic Dispensary” MH RT.
Results. Among patients with acute intestinal obstruction in colorectal cancer, a constant increase of the ration of elderly and senile patients is observed, as well as high anesthesia risk. Statistically significant indices of decrease of nutritional status in the group of patients of elderly and senile age and subtle manifestations of hypovolemia were revealed. In the elderly and senile patient group, polypragmasia was registered in 50.5 %.
Conclusion. Patients with colorectal cancer complicated by acute intestinal obstruction, have their own characteristics, different from patients operated on in clinics of urgent abdominal surgery with other diagnoses, the main ratio of which is made up of acute inflammatory diseases. This category of patients should be operated on in institutions where it is possible to provide specific highly skilled surgical and anesthesia-resuscitation care for malignant neoplasms.
colorectal cancer / intestinal obstruction / elderly and senile age / nutritional status / pathological thrombus formation / anesthesia risk / polypragmasia
| [1] |
Akhmetzyanov F.Sh., Valiev N.A., Egorov V.I., et al. Urgent surgery of intestinal obstruction due to colorectal cancer. Rossiyskiy zhurnal gastroenterologii, gepatologii, koloproktologii. 2018; 28 (1): 99–106. (In Russ.) |
| [2] |
Ахметзянов Ф.Ш., Валиев Н.А., Егоров В.И. и др. Тактика экстренного хирургического лечения обтурационной кишечной непроходимости, обусловленной колоректальным раком. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2018; 28 (1): 99-106. DOI: 10.22416/1382-4376-2018-28-1-99-106. |
| [3] |
Min C.K., Kim H.O., Lee D., et al. Obstructive left colon cancer should be managed by using a subtotal colectomy instead of colonic stenting. Ann. Coloproctol. 2016; 32 (6): 215–220. DOI: 10.3393/ac.2016.32.6.215. |
| [4] |
Min C.K., Kim H.O., Lee D., et al. Obstructive left colon cancer should be managed by using a subtotal colectomy instead of colonic stenting. Ann. Coloproctol. 2016; 32 (6): 215-220. DOI: 10.3393/ac.2016.32.6.215. |
| [5] |
Shchaeva S.N. Surgical treatment of colorectal cancer complicated with acute intestinal obstruction. Onkologicheskaya koloproctologiya. 2016; 6 (3): 8–16. (In Russ.) |
| [6] |
Щаева С.Н. Хирургическое лечение колоректального рака, осложненного острой кишечной непроходимостью. Онкологическая колопроктология. 2016; 6 (3): 8-16. . doi: 10.17650/2220-3478-2016-6-3-8-16. |
| [7] |
Shevchenko Yu.L., Stoykо Yu.М., Levchuk А.L., et al. Соmbination of complicated forms of the colon cancer: clinics, diagnostics, surgical tactics. Vestnik eksperimental’noy i klinicheskoy khirurgii. 2011; 4 (4): 641–646. (In Russ.) |
| [8] |
Шевченко Ю.Л., Стойко Ю.М., Левчук А.Л. и др. Сочетание осложненных форм рака толстой кишки: клиника, диагностика, хирургическая тактика. Вестник экспериментальной и клинической хирургии. 2011; 4 (4): 641-646. |
| [9] |
Amelung F.J., Consten E.C., Siersema P.D., et al. A population-based analysis of three treatment modalities for malignant obstruction of the proximal colon: acute resection versus stent or stoma as a bridge to surgery. Ann. Surg. Oncol. 2016; 23 (11): 3660–3668. DOI: 10.1245/s10434-016-5247-7. |
| [10] |
Amelung F.J., Consten E.C., Siersema P.D., et al. A population-based analysis of three treatment modalities for malignant obstruction of the proximal colon: acute resection versus stent or stoma as a bridge to surgery. Ann. Surg. Oncol. 2016; 23 (11): 3660-3668. DOI: 10.1245/s10434-016-5247-7. |
| [11] |
Gorobets E.S. Principles of anesthesia in abdominal oncology operations. Regional'naya anesteziya i lechenie ostroy boli. 2009; 2: 32–42. (In Russ.) |
| [12] |
Горобец Е.С. Принципы анестезии при абдоминальных онкологических операциях. Региональная анестезия и лечение острой боли. 2009; 2: 32-42. |
| [13] |
Musaeva T.S., Karipidi M.K., Zabolotskikh I.B. The significance of the cumulative balance in the development of early complications after extensive abdominal operation. Anesteziologiya i reanimatologiya. 2016; 61 (6): 422–425. (In Russ.) |
| [14] |
Мусаева Т.С., Карипиди М.К., Заболотских И.Б. Значимость кумулятивного баланса в развитии ранних осложнений после обширных абдоминальных операций. Анестезиология и реаниматология. 2016; 61 (6): 422-425. DOI: 10.18821/0201-7563-2016-6-422-425. |
| [15] |
Pasechnik I.N., Skobelev E.I., Smeshnoy I.A., Gubaydullin R.R. Problems of perioperative infusion therapy. Meditsinskiy alfavit. 2015; 4 (20): 14–19. (In Russ.) |
| [16] |
Пасечник И.Н., Скобелев Е.И., Смешной И.А., Губайдуллин Р.Р. Проблемы периоперационной инфузионной терапии. Медицинский алфавит. 2015; 4 (20): 14-19. |
| [17] |
Morita S., Ikeda K., Komori T., et al. Outcomes in Colorectal Surgeon-Driven Management of Obstructing Colorectal Cancers. Dis. Colon. Rectum. 2016; 59 (11): 1028–1033. DOI: 10.1097/DCR.0000000000000685. |
| [18] |
Morita S., Ikeda K., Komori T., et al. Outcomes in Colorectal Surgeon-Driven Management of Obstructing Colorectal Cancers. Dis. Colon. Rectum. 2016; 59 (11): 1028-1033. DOI: 10.1097/DCR.0000000000000685. |
| [19] |
Veyler R.V., Musaeva T.S., Trembach T.S., et al. Critical incidents during combined anesthesia with extensive abdominal operations in elderly and senile patients: the role of the preoperative level of wakefulness. Anesteziologiya i reanimatologiya. 2016; 61 (5): 352–365. (In Russ.) |
| [20] |
Вейлер Р.В., Мусаева Т.С., Трембач Т.С. и др. Критические инциденты в течение комбинированной анестезии при обширных абдоминальных операциях у пациентов пожилого и старческого возраста: роль предоперационного уровня бодрствования. Анестезиология и реаниматология. 2016; 61 (5): 352-365. DOI: 10.18821/0201-7563-2016-61-5-352-356. |
| [21] |
Sychev D.A., Otdelenov V.A., Krasnova N.M., et al. Polypragmasy: a clinical pharmacologist's view. Terapevticheskiy arkhiv. 2016: 88 (12); 94–102. (In Russ.) |
| [22] |
Сычев Д.А., Отделенов В.А., Краснова Н.М. и др. Полипрагмазия: взгляд клинического фармаколога. Терапевтический архив. 2016; 88 (12); 94-102. DOI: 10.17116/terarkh2016881294-102. |
| [23] |
Jyrkkä J., Enlund H., Korhonen M., et al. Polypharmacy Status as an Indicator of Mortality in an Elderly Population. Drugs & Aging. 2009; 26 (12): 1039–1048. doi: 10.2165/11319530-000000000-00000. |
| [24] |
Jyrkkä J., Enlund H., Korhonen M., et al. Polypharmacy Status as an Indicator of Mortality in an Elderly Population. Drugs & Aging. 2009; 26 (12): 1039-1048. doi: 10.2165/11319530-000000000-00000. |
| [25] |
Neymark M.I., Zhukov A.S. Ways of improving the efficacy of preoperative preparation in patients with acute intestinal obstruction. Vestnik khirurgii imeni I.I. Grekova. 2014; 173 (3): 68–71. (In Russ.) |
| [26] |
Неймарк М.И., Жуков А.С. Пути повышения эффективности предоперационной подготовки у пациентов с острой кишечной непроходимостью. Вестник хирургии им. И.И. Грекова. 2014; 173 (3): 68-71. DOI: 10.24884/0042-4625-2014-173-3-68-71. |
| [27] |
Ihedioha U., Gravante G., Lloyd G., et al. Curative colorectal resections in patients aged 80 years and older: clinical characteristics, morbidity, mortality and risk factors. Int. J. Colorectal. Dis. 2013; 28 (7): 941–947. DOI: 10.1007/s00384-012-1626-0. |
| [28] |
Ihedioha U., Gravante G., Lloyd G., et al. Curative colorectal resections in patients aged 80 years and older: clinical characteristics, morbidity, mortality and risk factors. Int. J. Colorectal. Dis. 2013; 28 (7): 941-947. DOI: 10.1007/s00384-012-1626-0. |
| [29] |
Lakhin R.E. Ultrasound in anesthesiology and resuscitation: what to teach? Anesteziologiya i reanimatologiya. 2016; 4: 25–27. (In Russ.) |
| [30] |
Лахин Р.Е. Ультразвук в анестезиологии и реаниматологии: чему учить? Анестезиология и реаниматология. 2016; 4: 25-27. . DOI: 10.18821/0201-7563-2016-4-263-265. |
| [31] |
Hoste E.A., Maitland K., Brudney C.S., et al. Four phases of intravenosus fluid therapy: a conceptual model. Br. J. Anaesth. 2014; 113: 740–747. DOI: 10.1093/bja/aeu300. |
| [32] |
Hoste E.A., Maitland K., Brudney C.S., et al. Four phases of intravenosus fluid therapy: a conceptual model. Br. J. Anaesth. 2014; 113: 740-747. DOI: 10.1093/bja/aeu300. |
| [33] |
Marik P.E. Iatrogenic salt water drowning and the hazards of a high central venous pressure. Ann. Intensive Care. 2014; 4: 21. doi: 10.1186/s13613-014-0021-0. |
| [34] |
Marik P.E. Iatrogenic salt water drowning and the hazards of a high central venous pressure. Ann. Intensive Care. 2014; 4: 21. DOI: 10.1186/s13613-014-0021-0. |
| [35] |
Relation Between IVC/RA junction and Central Venous Pressure (CVP) Adapted from Jones Handbook of Ultrasound in Trauma and Critical Care Illness, 2003. |
| [36] |
Relation Between IVC/RA junction and Central Venous Pressure (CVP) Adapted from Jones Handbook of Ultrasound in Trauma and Critical Care Illness, 2003. |
| [37] |
Pasheev A., Sayetgaraev A., Muftahutdinova G. The impact of prewarming on core temperature a hypothermia in oncogynecologal surgery. Eur. J. Anaesthesiol. 2017; 34 (55): 357. |
| [38] |
Akhmetzyanov F.Sh, Shaymardanov I.V., Pasheev A.V., et al. Prevention and treatment of unintended perioperative hypothermia. Kazanskiy meditsinskiy zhurnal. 2018; 99 (1): 70–78. (In Russ.) |
| [39] |
Ахметзянов Ф.Ш., Шаймарданов И.В., Пашеев А.В. и др. Профилактика и лечение непреднамеренной периоперационной гипотермии. Казанский медицинский журнал. 2018; 99 (1): 70-78. DOI: 10.17816/ KMJ2018-070. |
| [40] |
KMJ2018-070. |
| [41] |
Torossian A., Bräuer A., Höcker J., et al. Clinical practice guideline: preventing inadvertent perioperative hypothermia. Dtsch. Arztebl. Int. 2015; 112: 166-172. PMID: 25837741. |
| [42] |
Torossian A., Bräuer A., Höcker J., et al. Clinical practice guideline: preventing inadvertent perioperative hypothermia. Dtsch. Arztebl. Int. 2015; 112: 166–172. PMID: 25837741. |
| [43] |
Ахметзянов Ф.Ш., Шаймарданов И.В, Шайхутдинов Н.Г., Егоров В.И. Опыт оказания неотложной и паллиативной медицинской помощи онкологическим больным в ГАУЗ РКОД МЗ РТ. Поволжский онкологический вестник. 2017; 31 (4): 35-39. |
| [44] |
Akhmetzyanov F.Sh., Shaymardanov I.V, Shaykhutdinov N.G., Egorov V.I. Experience in providing emergency and palliative care to cancer patients at the GAUZ RKOD MZ RT. Povolzhskiy onkologicheskiy vestnik. 2017; 31 (4): 35–39. (In Russ.) |
| [45] |
Ахметзянов Ф.Ш., Егоров В.И. Оптимизация хирургического лечения пациентов после обструктивных резекций толстой кишки. Новости хирургии. 2017; 25 (5): 488-493. DOI: 10.18484/2305-0047.2017.5.488. |
| [46] |
Akhmetzyanov F.Sh., Egorov V.I. Optimization of surgical treatment of patients undergoing obstructive colonic resection. Novosti khirurgii. 2017; 25 (5): 488–493. (In Russ.) |
| [47] |
Edington J. Prevalence of malnutrition on admission to four hospitals in England. The Malnutrition Prevalence Group. J. Clin. Nutr. 2000; 19: 191-195. DOI: 10.1054/clnu.1999.0121. |
| [48] |
Edington J. Prevalence of malnutrition on admission to four hospitals in England. The Malnutrition Prevalence Group. J. Clin. Nutr. 2000; 19: 191–195. DOI: 10.1054/clnu.1999.0121. |
| [49] |
Гатауллин И.Г., Фролов С.А., Савинков В.Г. и др. Профилактика послеоперационной гиперкоагуляции у больных с колоректальным раком. Поволжский онкологический вестник. 2014; 2: 4-8. |
| [50] |
Gataullin I.G., Frolov S.A., Savinkov V.G., et al. Prevention of postoperative hypercoagulation in patients with colorectal cancer. Povolzhskiy onkologicheskiy vestnik. 2014; 2: 4–8. (In Russ.) |
Akhmetzyanov F.S., Saetgaraev A.K., Pasheev A.V., Valiev N.A., Levin M.V., Shaymardanov I.V., Sadykov K.K.
/
| 〈 |
|
〉 |