The rationale for the post-transfusion reactions prevention program in rh-positive patients

R G Turaev; E E Bel’skaya

doi:10.17816/KMJ1939

Kazan medical journal ›› 2013, Vol. 94 ›› Issue (5) : 764 -765. DOI: 10.17816/KMJ1939

Actual problems of biochemistry and laboratory diagnostics

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The rationale for the post-transfusion reactions prevention program in rh-positive patients

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Abstract

A case of a patient with А 2В (IV) Rh 0(D) + blood group, CcDEeK - phenotype, in whom anti-erythrocyte antibodies (+) were found and specified as anti-D antibodies, is presented. The Rh compatibility tests were positive with 28% Rh 0(D) +-donors (incompatibility) and negative with all Rh 0(D) --donors (compatibility) as well as with own erythrocytes (compatibility). The case indicates that a timely extensive examination of a patient’s blood (antigen profile examination with anti-erythrocyte antibodies detection) before blood transfusion guarantees the blood transfusion safety and reduces the rate of negative consequences of erythrocyte-containing blood components, including hemolytic reactions.

Keywords

Rh blood group system / RhD polymorphism / anti-erythrocyte antibodies / transfusion safety / gel method

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R G Turaev, E E Bel’skaya. The rationale for the post-transfusion reactions prevention program in rh-positive patients. Kazan medical journal, 2013, 94(5): 764-765 DOI:10.17816/KMJ1939

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