Clinical features of enteroviral infection in pregnancy

Abstract

Aim. To explore the modern clinical features of enteroviral infection in pregnancy. Methods. Comprehensive survey of 262 pregnant women was carried out. 203 patients were diagnosed with enteroviral infection, control group consisted of 59 pregnant women without enteroviral infection. All patients underwent ultrasonic fetometry, cardiotocography, placentography, ultrasonic fetometry, amniotic fluid quantitative and qualitative analysis, feto-placental, utero-placental and fetal circulation Doppler ultrasound. Results. Asymptomatic form of enteroviral infection was more frequently found in pregnant women aged 30-39 years, typical and atypical forms - in the age group of 20-29 years. The onset of menarche and the duration of the menstrual cycle were not associated with the risk for enteroviral infection. Enteroviral infection was often seen in combination with other infections and gynecological diseases. The rate of multi-infection was significantly higher in the group with typical form of entroviral infection, while atypical form of infection were mostly seen along with comorbidities. Conclusion. Immune status has a great influence on developing of clinically manifesting forms of enteroviral infection in pregnant women. Co-existence of enteroviral infection with other infectious and gynecological diseases may alter the clinical features, lead to development of atypical forms and become a significant burden to the pregnancy.

Keywords

gynecological diseases / enteroviral infections / pregnancy

References

[1] Алёшкин В.А., Афанасьев С.С. Состояние иммунной системы у беременных и новорождённых группы высокого риска по внутриутробному инфицированию // Рос. вестн. перинатал. и педиатр. - 2004. - №6. - С. 10-16.

[2] Игнатко И.В., Рыбин М.В., Дуболазов В.Д. Профилактика плацентарной недостаточности у беременных группы высокого риска // Вопр. гинекол., акушер. и перинатол. - 2006. - №7. - С. 11-20.

[3] Hay P.E., Lamont R.F., Taylor-Robinson D., Monte N. Abnormal bacterial colonization of the genital tract and subsequent preterm delivery and late miscarriage // Br. J. Med. - 2009. - Vol. 308, N 1. - P. 295-298.

[4] Kozovsky I. Cesarean section in modern obstetrics and methods of prophylaxis of prospective sepsis // Akush. Ginecol. (Sofia). - 2007. - Vol. 39, N 3. - P. 3-6.

[5] Perez A., Labbok M.H., Gueenan J.Т. Infection control // Lancet. - 2006. - Vol. 339, N 4. - P. 968-970.

RIGHTS & PERMISSIONS

Geydarova N.F.