Determining the efficacy of complex conservative treatment of chronic constipation in children

Abstract

Aim. Evaluation of the effectiveness of complex conservative treatment of chronic constipation in children of different age groups.

Methods. Results of conservative treatment for chronic constipation in 574 children in different age groups are presented in the article. 321 of those were assigned to traditional treatment (group 1), while 248 were assigned consecutively to metronidazole, intesti-bacteriofague, probiotics along with traditional treatment for more adequate therapy; to magnesium orotate - to correct microcirculatory disorders and tissue dysplasia; to prevent and treat endogenic intoxication and secondary hepatic disease - to glutathione (group 2). The treatment was conducted for a year by courses in months 1, 2, 3, 6, 9 and 12 (total of 6 courses). If ineffective, follow-up treatment was provided: within 2 years - quarterly (4 courses) and during the third year - once in 6 months (2 courses).

Results. Compared to traditional treatment the results of the suggested complex treatment were sifgnificantly better; the best results were achieved in age group 3-7 years; stable and positive result was achieved already by the end of the first year of suggested complex treatment, and with traditional approach the duration of treatment was up to 3 years.

Keywords

chronic constipation / efficacy of conservative treatment / children

References

[1] Дубровская М.И., Шумилов П.В., Мухина Ю.Г. Запоры у детей: современные подходы и тактика лечения. Леч. врач. 2008; (7): 28-30.

[2] Kirgizov I.V., Minaev S.V. The ultrasonic way of the intraoperative assess of the resection volume of colon in children with chronic constipation. Med. News North Caucasus. 2014; 9 (2): 125-128. DOI: 10.14300/mnnc.2014.09035.

[3] Мельникова И.Ю., Новикова В.П., Думова Н.Б. Запоры у детей. Руководство. М.: ГЭОТАР-Медиа. 2015; 164 с.

[4] Лёнюшкин А.И., Киргизов И.В. Новая концепция этиопатогенеза хронических запоров у детей и принципы их лечения. Вопр. соврем. педиатрии. 2006; 5 (4): 49-54.

[5] Bischoff A., Martinez-Leo B., Peña A. Laparoscopic approach in the management of anorectal malformations. Pediatric Surg. Intern. 2015; 31 (5): 431-437. DOI: 10.1007/s00383-015-3687-y.

[6] Татьянина О.Ф. Современные антибактериальные препараты: новые возможности в профилактике дисбиотических нарушений. Вопр. соврем. педиатрии. 2011; 10 (6): 77-82.

[7] Блат С.Ф., Хавкин А.И. Микробиоценоз кишечника и иммунитет. Рос. вестн. перинатол. и педиатрии. 2011; 56 (1): 159-174.

[8] Полухов Р.Ш. Изменения илеоцекального клапана при хроническом запоре у детей. Клинична хирургия. 2012; (2): 42-44. DOI: 616.352-008.22.

RIGHTS & PERMISSIONS

Polukhov R.S.