Factors influencing survival of patients suffering from nonspecific aortoarteritis

Abstract

Aim. To identify the factors influencing survival of patients with Takayasu arteritis with the use of Kaplan-Meier mono-factor analysis.

Methods. As the factors influencing survival we analyzed gender, smoking status, tachycardia, arterial hypertension, comlications, left common iliac artery involvement, character of disease progression, and social factors. 96 patients suffering from nonspecific aortoarteritis and observed in Regional clinical hospital №1 in 1998-2016 were examined.

Results. Survival of patients suffering from nonspecific aortoarteritis was influenced by: male gender (p=0.0030), smoking (р=0.00762), tachycardia at the time of diagnosis (p=0.01762), arterial hypertension at the time of diagnosis (p=0.04150), involvement of left common iliac artery (p=0.02970), more than 3 complications (p=0.00062), progressive course of the disease (p=0.00016), being divorced (p=0.00018). 5-year survival was 99%, 10-year survival - 95%, 15-year survival - 93%.

Conclusion. The following factors were identified as influencing survival of patients with Takayasu arteritis: male gender, smoking, tachycardia and arterial hypertension at the time of diagnosis, involvement of left common iliac artery, more than 3 complications, progressive course of the disease and being divorced.

Keywords

nonspecific aortoarteritis / survival / risk / prognosis

RIGHTS & PERMISSIONS

Borodina I.E., Shardina L.A.