Effective treatment of septic shock using oXiris-therapy in a patient with diffuse fecal peritonitis and severe comorbid background

Abstract

To assess the efficiency of using the methods of extracorporeal detoxification in the complex treatment of sepsis and septic shock so as to eliminate endotoxin, cytokines as well as to replace the function of organs. The article presents a successful experience of using two sessions of hemofiltration with an oXiris set for extrarenal indications in a patient with diffuse fecal peritonitis and severe comorbid background after surgery. The complex of therapeutic measures, dynamics of clinical and laboratory data before and after both sessions of oXiris therapy is presented. Positive effect of hemofiltration on the patient's condition using the oXiris set was noted 48–72 hours after the start of the procedure and 72 hours after its completion. The use of two sessions of oXiris therapy in the treatment of septic shock in a patient with diffuse fecal peritonitis and severe comorbid background allowed stabilizing hemodynamics 48–72 hours after the start of treatment; a significant improvement of a patient’s condition occurred 72 hours after the end of the second procedure.

Keywords

abdominal sepsis / septic shock / multiple organ failure / endotoxin activity / oXiris set

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