Pregnancy management tactics in fetal hemolytic disease. Literature review
M. V. Fedchenko , Yu. S. Maslennikova
Perm Medical Journal ›› 2020, Vol. 37 ›› Issue (6) : 71 -80.
Pregnancy management tactics in fetal hemolytic disease. Literature review
Hemolytic disease of the fetus is one of the types of pathological abnormalities in the development of the fetus, the reason of which is isoimmune hemolytic anemia. Depending on the degree of severity of this pathology, it can influence the development of the fetus both in a mild form, practically leaving no trace and in a severe form, which can cause fetal death.
When carrying out a timely diagnostic research to detect this pathology, tactics of pregnancy management should differ, that will allow maintaining of pregnancy and ensure normal development of the fetus just until the moment of childbirth. To determine the tactics, which will be used during pregnancy management, it is necessary to identify not only the symptoms of hemolytic diseases of the fetus but its degree as well. Depending on the degree of severity of this disease, the activities will differ. If the disease is developing in a mild form, a pregnant woman is thoroughly observed and repeatedly diagnosed; if it is a severe form, intrauterine fetal blood transfusions are regularly conducted. The tactics of managing pregnancy with the detected fetal hemolytic disease will differ from the standard one and its right choice will ensure normal development of the fetus and term labor with minimum risks for both a mother and a child.
Pregnancy / fetal hemolytic disease / pathology / antibodies / sensitization
| [1] |
Gleason C.A., Devaskar S.U. Avery’s diseases of the newborn. 9th Ed. Elsevier Saunders. 2011; 1520. |
| [2] |
Gleason C.A., Devaskar S.U. Avery’s diseases of the newborn. 9th Ed. Elsevier Saunders 2011; 1520. |
| [3] |
Gomella T.L. Neonatology: management, procedures, on-call problems, diseases, and drugs. 7th ed. Medical Publishing Division 2013; 1113. |
| [4] |
Volodin N.N. Neonatology. National guide: short edition. Moscow: GEOTAR-Media 2013; 896 in Russian). |
| [5] |
Неонатология: национальное руководство: краткое издание. Под ред. Н.Н. Володина. М.: ГЭОТАР-Медиа 2013; 896. |
| [6] |
Savelyeva G.M. Rhesus – sensitization. Hemolytic disease of the fetus. Clinical guidelines protocol). Under. ed. G.M. Savelyeva – Letter from the Ministry of Health dated 05/18/2017. No. 15-4 / 10 / 2-3300 in Russian), available at: http://www.transfusion.ru/ 2017/08-09-2.pdf. |
| [7] |
Резус-сенсибилизация. Гемолитическая болезнь плода: клинические рекомендации протокол). Под. ред. Г.М. Савельевой. Письмо Министерства здравоохранения от 18.05.2017 г. № 15–4/10/2–3300, available at: http://www.transfusion.ru/2017/08-09-2.pdf |
| [8] |
Meghan Delaney, Dana C. Matthews Hemolytic disease of the fetus and newborn: managing the mother, fetus, and newborn Great expectations: hematology in pregnancy. December 5, 2015. available at: https://ashpublications.org/hematology/article/2015/1/146/20756/Hemolytic-disease-of-the-fetus-and-newborn |
| [9] |
Kaplan M., Na’amad M., Kenan A. et al. Failure to predict hemolysis and hyper bilirubinemia by IgG subclass in blood group A or B infants born to group O mothers Pediatrics 2009; 123 1): e132–e137in Russian). |
| [10] |
Kaplan M., Na’amad M., Kenan A. et al. Failure to predict hemolysis and hyperbi lirubinemia by IgG subclass in blood group A or B infants born to group O mothers. Pediatrics 2009; 123 1): e132–e137. |
| [11] |
Hemolytic disease of the fetus in pregnant women with Rh-sensitization. Diagnostics, treatment, prevention Letter of the Ministry of Health and Social Development of the Russian Federation of December 16, 2011 No. 15-4 / 10 / 2-12699, available at: http://docs.cntd.ru/ document/902328227in Russian). |
| [12] |
Гемолитическая болезнь плода у беременных с резус-сенсибилизацией. Диагностика, лечение, профилактика: письмо Министерства здравоохранения и социального развития РФ от 16.12.2011 № 15-4/10/2-12699, available at: http://docs.cntd.ru/document/902328227 |
| [13] |
Gleason C.A., Devaskar S.U. Avery’s diseases of the newborn. 9th Ed. Elsevier Saunders. 2011; 1520. |
| [14] |
Sinha S., Miall L., Jardine L. Essential neonatal medicine. 5th ed. Wiley-blackwell 2012; 388. |
| [15] |
Markelova A.N., Melnikov V.A., Tyumina O.V. The possibility of perinatal diagnosis of the Rh factor of the fetus by the blood of a pregnant woman. Fundamental'nye issledovanija 2012; 122): 298–300 in Russian). |
| [16] |
Маркелова А.Н., Мельников В.А., Тюмина О.В. Возможность перинатальной диагностики резус-фактора плода по крови беременной женщины. Фундаментальные исследования 2012; 12 2): 298–300. |
| [17] |
Beluga M.V. Diagnostics and intrauterine correction of anemia in fetal hemolytic disease. Zhurnal Grodnenskogo gosudarstvennogo medicinskogo universiteta 2012; 2: 37–40 in Russian). |
| [18] |
Белуга М.В. Диагностика и внутриутробная коррекция анемии при гемолитической болезни плода. Журнал Гродненского государственного медицинского университета 2012; 2: 37–40. |
| [19] |
American Assocation of Blood Banks. Ed 18 Bethesda, MDAABB Press Technical Manual 2014. |
| [20] |
American Assocation of Blood Banks. Ed 18 Bethesda, MDAABB Press Technical Manual 2014 |
| [21] |
Ivanova A.V., Zakharova S.Yu., Kosov tsova N.V., Pavlichenko M.V., Generalov A.E. Features of the course of the neonatal period in newborns who received intrauterine intravascular blood transfusion for hemolytic disease of the fetus. Rossijskij vestnik perinatologii i pediatrii 2015; 1: 44–48 in Russian). |
| [22] |
Иванова А.В., Захарова С.Ю., Косовцова Н.В., Павличенко М.В., Генералов А.Е. Особенности течения неонатального периода у новорожденных, получивших внутриутробное внутрисосудистое переливание крови по поводу гемолитической болезни плода. Российский вестник перинатологии и педиатрии 2015; 1: 44–48. |
| [23] |
Sheybak L.N. Modern ideas about the features of hemolytic disease of the fetus and newborn. Zhurnal Grodnenskogo gosudarstven nogo medicinskogo universiteta 2015; 1 in Russian). |
| [24] |
Шейбак Л.Н. Современные представления об особенностях гемолитической болезни плода и новорожденного. Журнал Гродненского государственного медицинского университета 2015; 1. |
| [25] |
Mikhailov, A.V., Konstantinova T.V., Pigina N.M. Intrauterine blood transfusions to the fetus as a method of treating the edematous form of hemolytic disease. Akusherstvo i ginekologija 1990; 7: 41–44 in Russian). |
| [26] |
Михайлов А.В., Константинова Н.М., Пигина Т.В. Внутриматочные переливания крови плоду как способ лечения отечной формы гемолитической болезни. Акушерство и гинекология 1990; 7: 41–44. |
| [27] |
GloriaTooRichard L.Berkowitz Obstetric Imaging: Fetal Diagnosis and Care Second Edition) 2018; 475–478.e1. |
| [28] |
GloriaTooRichard L. Berkowitz Obstetric Imaging: Fetal Diagnosis and Care Second Edition) 2018; 475–478.e1. |
| [29] |
Savelyeva G.M. Rhesus is a sensitization. Hemolytic disease of the fetus: diagnosis, treatment, prevention. Ways to reduce infant morbidity and mortality methodological recommendations) Moscow: RAMS 2019; 48 in Russian). |
| [30] |
Савельева Г.М. Резус-сенсабили зация. Гемолитическая болезнь плода: диагностика, лечение, профилактика. Пути снижения младенческой заболеваемости и смертности: методические рекомендации. М.: РАМН 2019; 48. |
| [31] |
Fatemeh Tara, Marzieh Lotfalizadeh, Somayeh Moeindarbari Electron Physician 2016 Aug, available at: https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5053461/ |
| [32] |
Fatemeh Tara, Marzieh Lotfalizadeh, Somayeh Moeindarbari Electron Physician. 2016, available at: https://www.ncbi.nlm.nih.gov/ pmc/articles/PMC5053461/ |
| [33] |
Ailamazyan E.K., Kulakov V.I., Radzinsky V.E., Savelyeva G.M. Obstetrics: national guidance. Moscow: GEOTAR – Media 2013; 1200 in Russian), available at: https://www.ulsu.ru/media/uploads/nina-bara tyuk %40mail.ru/2017/01/10/national_ leadership_in_obstetrics_2013.pdf |
| [34] |
Акушерство: национальное руководство. Под ред. Э.К. Айламазяна, В.И. Кулакова, В.Е. Радзинского, Г.М. Савельевой. М.: ГЭОТАР-Медиа 2013; 1200, available at: https://www.ulsu.ru/media/uploads/nina-baratyuk%40mail.ru/2017/01/10/national_leadership_in_obstetrics_2013.pdf |
| [35] |
Degtyareva A.V., Degtyarev D.N., Karpova A.L., Karpov N.Yu., Senkevich O.A., Son E.D. Draft clinical guidelines for the diagnosis and treatment of hemolytic disease in newborns. Neonatologija: novosti, mnenija, obuchenie 2015; 2: 87–101 in Russian). |
| [36] |
Дегтярева А.В., Дегтярев Д.Н., Карпова А.Л., Карпов Н.Ю., Сенькевич О.А., Сон Е.Д. Проект клинических рекомендаций по диагностике и лечению гемолитической болезни новородженных. Неонатология: новости, мнения, обучение 2015; 2: 87–101. |
| [37] |
Roose R. Genzel-Borovicheni O. Neonatology. Practical recommendations: translation from German. Moscow: Med. lit. 2011; 592 in Russian). |
| [38] |
Рооз Р., Генцель-Боровичени О., Прокитте Г. Неонатология: практические рекомендации: пер. с нем. М.: Мед. лит. 2011; 592. |
| [39] |
Ozhereleva M.A., Kravchenko E.N., Vetrov V.V., Ivanov D.O., Kuklina L.V. Prevention of hemolytic disease of the fetus and newborn and its severe forms in Rh-conflict. Detskaja medicina Severo-Zapada 2015; 3 6): 42–48 in Russian). |
| [40] |
Ожерельева М.А., Кравченко Е.Н., Ветров В.В., Иванов Д.О., Куклина Л.В. Профилактика гемолитической болезни плода и новорожденного и ее тяжелых форм при резус-конфликте. Детская медицина Северо-Запада 2015; 3 6): 42–48. |
| [41] |
Kotikovich Yu.S. A new strategy for the prevention of hemolytic disease of newborns. Ukraїns'kij medichnij chasopis. Aktual'nі pitannja klіnіchnoї praktiki 2013; 2 94) in Ukrainian). |
| [42] |
Котикович Ю.С. Новая стратегия про филактики гемолитической болезни новорожденных. Український медичний часопис. Акту альні питання клінічної практики 2013; 2 94). |
Fedchenko M.V., Maslennikova Y.S.
/
| 〈 |
|
〉 |