Coinfection of gastric mucosa with Helicobacter Pylori and Epstein-Barr virus as a factor of ineffectiveness of antihelicobacter chronic gastritis therapy in adolescents

I. S. Akkuratova; E. M. Spivak; O. M. Manyakina

doi:10.17816/pmj36127-30

Perm Medical Journal ›› 2019, Vol. 36 ›› Issue (1) :27 -30. DOI: 10.17816/pmj36127-30

Clinical studies

research-article

Coinfection of gastric mucosa with Helicobacter Pylori and Epstein-Barr virus as a factor of ineffectiveness of antihelicobacter chronic gastritis therapy in adolescents

Author information +

History +

PDF

Abstract

Aim. To assess the character of bacterial-viral infection of the gastric mucosa and dynamics of inflammatory process in adolescents with chronic gastritis in case of antihelicobacter therapy failure.

Materials and methods. Seventy two adolescents with chronic gastritis aged 11–18 years (mean age 13.8 ± 0.4) were examined prior to and after antihelicobacter therapy.

Results. It was established that after treatment against the background of regression of clinical symptoms, in most patients no positive dynamics of process manifestation or its progression was noted both in the body and antral part of the stomach.

Conclusions. In the absolute majority of adolescents with the absence of Hp eradication (78.7 %) there was observed colonization with positive Hp strains and persistence of Epstein-Barr virus (68.1 %). It allows considering patients with such co-infection as a risk group for the absence of Hp eradication.

Keywords

Chronic gastritis / Helicobacter pylori / Epstein-Barr virus / treatment / adolescents

Cite this article

Download citation ▾

I. S. Akkuratova, E. M. Spivak, O. M. Manyakina. Coinfection of gastric mucosa with Helicobacter Pylori and Epstein-Barr virus as a factor of ineffectiveness of antihelicobacter chronic gastritis therapy in adolescents. Perm Medical Journal, 2019, 36(1): 27-30 DOI:10.17816/pmj36127-30

登录浏览全文

4963

注册一个新账户忘记密码

References

Publishing order | Descend order by publishing year | Descend order by cited within

[1]	Нижевич А.А., Валеева Д.С. Инфекция Helicobacter pylori в детском возрасте: современные аспекты диагностики и лечения. Болезни желудка и двенадцатиперстной кишки у детей. М.: МЕДПРАКТИКА-М 2017: 129–187.

[2]	Новикова В.П. Этиопатогенетические и клинико-морфологические особенности хронического гастрита в разном возрасте: автореф. дис. … д-ра мед. наук. СПб. 2009: 48.

[3]	Крулевский В.А., Петровский А.Н., Новикова В.П. Цитогенетические нарушения в желудочном эпителии у больных с хроническим гастритом, ассоциированным с инфицированием вирусом Эпштейна – Барр. Врач-аспирант 2011; 2: 355–359.

[4]	Спивак Е.М., Левит Р.М., Аккура това И.С., Надежин А.С. Хронический гастродуоденит у детей: клинические варианты, особенности диагностики и лечения. Ярославль: Филигрань 2016: 172.