Inflammatory bowel diseases: course peculiarities and drug therapy in pregnant women. Lactation. Personal matters (by the materials of the second european consensus on reproduction and pregnancy in patients with inflammatory bowel diseases, 2015)

Abstract

The paper presents a continuation of discussion regarding personal matters on the course of inflammatory bowel diseases (IBD) such as ulcerative colitis (UC) and Crohn’s disease (KD) in pregnant women, including the problems of basic drug therapy of the main disease both during pregnancy and lactation period. Separately, there are data on safety of conducted therapy, indications for surgical treatment and use of biological genetically engeneered drugs. The paper is based on the materials of “The Second European Consensus on Reproduction and Pregnancy in Patients with Inflammatory Bowel Diseases, 2015”. The main positions are presented according to the criteria of evidence-based medicine.

Keywords

pregnancy / inflammatory bowel diseases / ulcerative colitis / Crohn’s disease / drug therapy / lactation / surgical treatment

References

[1] Успенская Ю.Б. Воспалительные заболевания кишечника и беременность: научно-практическая монография. М. 2015; 40.

[2] Халиф И.Л., Шелыгин Ю.А. Воспалительные заболевания кишечника: диагностика и лечение: атлас. СПб.: Гиппократ 2017; 106-111.

[3] Циммерман Я.С., Михалева Е.Н. Возможности фармакотерапии при лечении гастроэнтерологических заболеваний во время беременности. Клиническая медицина 2015; 8: 8-18.

[4] The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease. Journal of Crohn's and Colitis; 2015: 1-18.

RIGHTS & PERMISSIONS

Khlynova O.V., Sandakova E.A., Zitta D.V., Stepina E.A., Koposova K.A., Okisheva L.G.