DYNAMICS OF PSYCHOPATHOLOGICAL SYMPTOMS IN PATIENTS WITH DISTURBANCES OF SСHIZOPHRENIC SPECTRUM UNDERGOING COMPULSORY TREATMENT AT GENERAL TYPE MENTAL HOSPITAL

Abstract

Aim. To assess the manifestation and dynamics of psychopathological symptoms by positive and negative symptoms scale (PANSS) in 82 patients with schizophrenia and disturbances of schizophrenic spectrum undergoing a course of compulsory treatment at the mental hospital of general type taking into account gender peculiarities. Materials and methods. The results of observation of 62 patients undergoing a course of treatment at the mental hospital of general type were studied. Paranoid form of schizophrenia prevailed irrespective of a gender composition. Manifestation and dynamics of psychopathological symptomatology was assessed using PANSS. To register the data, PANSS signs reflected in three subscales (positive, negative and general pathological) as well as total summary score were applied. The data were estimated at the beginning of hospitalization and at the moment of discharge from hospital. Results. Manifestation of psychopathological symptoms at admission to hospital was significantly higher ( p <0,001) in female patients (69,2±12,9 in women and 58,8±10,0 in men), predominantly at the expense of positive and general pathological symptoms. At the moment of discharge form hospital, women had a reduced manifestation of positive and general pathological symptoms with a reliable difference ( p <0,001) as compared to the admission symptoms. Among men, in spite of decreased PANSS values, this dynamics was less evident. By the moment of discharge from hospital, manifestation of general pathological symptoms in women (29,5±3,9) was higher than the analogous indices in men (25,6±5,3) with a reliable difference ( p <0,001). Conclusion. The reached relapse of mental disorders is one of the necessary conditions for assessment of the efficiency of compulsory treatment, however, it is not the only efficiency criterion. Individual-psychological peculiar features and social setting taken into account are not less important.

Keywords

mental hospital / gender peculiarities / psychopathological symptoms / compulsory treatment

References

[1] Березанцев А. Ю., Митрофанова О. И. Гендер, комплаенс и качество жизни больных шизофренией: аналитический обзор. Российский психиатрический журнал 2009; 1: 24–32.

[2] Винникова И. Н. Меры медицинской профилактики общественно-опасных действий больных шизофренией (терапевтические, реабилитационные и фармакоэкономические аспекты принудительного лечения): автореф. дис. … д-ра мед. наук. М. 2009; 35.

[3] Захаров Н. Б., Злоказова М. В., Соловьев А. Г. Гендерные особенности назначения психотропных препаратов при лечении шизофрении в психиатрическом стационаре. Психическое здоровье 2010; 7: 47–50.

[4] Качаева М. А., Русина В. В. Гендерные аспекты особенностей агрессивных преступлений, совершенных женщинами. Российский психиатрический журнал 2010; 6: 4–10.

[5] Усов Г. М. Общественная опасность лиц, страдающих психическими расстройствами (клинико-патогенетический и реабилитационный аспекты): автореф. дис. … д-ра мед. наук. М. 2008; 47.

RIGHTS & PERMISSIONS

Zakharov N.B.