LIPID DEGENERATION IN PHEOCHROMOCYTOMAS MIMICING ADRENOCORTICAL TUMORS (TWO observations)

Abstract

Lipid (fatty) degeneration occurs rare in pheochromocytomas. The paper presents description of two observations of adrenal pheochromocytoma with lipid degeneration. Histological and immunological studies proved accumulation of lipids in tumor cells. In the first observation, the following background diseases were noted: Sanarelli-Schwarzman syndrome, autoimmune thyroiditis, hypothyrosis, degree II-III obesity. In the second observation, taking into account local expression of tenascin-C, we can speak about uncertain potential of tumor malignancy. These observations are of special interest regarding differential diagnosis of pheochromocytoma with fatty degeneration and concurrent tumors (cortical adenoma and pheochromocytoma) and mixed tumors such as adenomas containing cortical substance cells (adenoma-pheochromocytoma)

Keywords

Adrenal glands / tumor / pheochromocytoma / fatty degeneration / histology / immunohistochemistry

References

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RIGHTS & PERMISSIONS

Kalinin A.P., Polyakova G.A., Britvin T.A., Bezuglova T.V.