COMPARATIVE CLINICONEUROPSYCHOLOGICAL ASSESSMENT OF COGNITIVE DISORDERS IN PATIENTS WITH ALZHEIMER’S DISEASE, VASCULAR AND MIXED COGNITIVE DISTURBANCES AT DIFFERENT STAGES OF COGNITIVE DEFICIENCY

Abstract

Aim. To compare clinical manifestations and neuropsychological profile of cognitive disorders in patients with Alzheimer’s disease, vascular and mixed vasculodegenerative cognitive disorders at different stages of cognitive deficiency. Materials and methods. In 106 patients of The Center of Cognitive Disorders the status of four cognitive domains including memory, speech, visual-spatial and regulatory-dynamic functions was estimated during complex neuropsychological examination. Results. The applied method of comparing of neuropsychological parameters of patients at the identical stage of cognitive deficiency showed that differences in cognitive profiles between the indicated groups depend on the stage of the process. Conclusion. Differential diagnosis of three considered in the paper cognitive disorders types can be completely performed only at the stage of moderate dementia with evaluation of episodic, semantic memory and visual-spatial functions.

Keywords

Cognitive disorders / Alzheimer’s disease / vascular cognitive disorders / mixed cognitive disorders

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RIGHTS & PERMISSIONS

Mantashova A.M.