ASSESSMENT OF EFFICIENCY OF COMPLEX TREATMENT OF PATIENTS WITH PERIODONTITIS BASED ON CLINICOROENTGENOLOGICAL AND BIOCHEMICAL INDICES

L E Leonova; A A Kovtun; G A Pavlova

doi:10.17816/pmj302103-108

Perm Medical Journal ›› 2013, Vol. 30 ›› Issue (2) :103 -108. DOI: 10.17816/pmj302103-108

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ASSESSMENT OF EFFICIENCY OF COMPLEX TREATMENT OF PATIENTS WITH PERIODONTITIS BASED ON CLINICOROENTGENOLOGICAL AND BIOCHEMICAL INDICES

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Abstract

Aim. To carry out comparative assessment of the efficiency of complex treatment of patients with chronic generalized periodontitis using drugs for osteotropic therapy. Materials and methods. Complex examination and treatment of 112 patients with chronic generalized periodontitis aged 20–49 was performed. In the main group (72 patients), complex treatment included the course of osteotropic therapy using a new drug «Calcium-vit D 3C» containing calcium carbonate 750 mg (equivalent to 300 mg of calcium), cholecalcipherol (vitamin D 3) 100 ME, ascorbic acid 50 mg, hips and licorice root extracts followed by gel «Holisal» application. In comparison group (40 patients), treatment was conducted applying the drug «Calcium D 3» (Nikomed , Norway) and 3% aspirin ointment. Results. Positive effect of treatment manifested by stabilization of pathological process in periodontium tissues of 75% of patients of the main group in the nearest and remote terms, reliable improvement of clinical roentgenological and biochemical indices was stated. Conclusion. Safety and efficiency of using «Calcium-vit D 3C» regarding blood serum total calcium, inorganic phosphorus and active-alkaline phosphatase content as well as dynamics of cytokine indices influencing periodontium bone tissue status was proved.

Keywords

OPG) / Chronic generalized periodontitis / osteotropic therapy / roengenological investigation / bone tissue density / blood serum total calcium / inorganic phosphorus and active-alkaline phosphatase content / cytokines (RANKL

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L E Leonova, A A Kovtun, G A Pavlova. ASSESSMENT OF EFFICIENCY OF COMPLEX TREATMENT OF PATIENTS WITH PERIODONTITIS BASED ON CLINICOROENTGENOLOGICAL AND BIOCHEMICAL INDICES. Perm Medical Journal, 2013, 30(2): 103-108 DOI:10.17816/pmj302103-108

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